Scheer Justin K, Mundis Gregory M, Klineberg Eric, Hart Robert A, Deviren Vedat, Burton Douglas C, Protopsaltis Themistocles S, Gupta Munish, Rolston John D, Bess Shay, Shaffrey Christopher I, Schwab Frank, Lafage Virginie, Smith Justin S, Ames Christopher P
Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2210, Chicago, IL, 60611, USA.
San Diego Center for Spinal Disorders, La Jolla, CA, USA.
Eur Spine J. 2016 Aug;25(8):2612-21. doi: 10.1007/s00586-015-3787-3. Epub 2015 Feb 6.
To identify the effect of complications and reoperation on the recovery process following adult spinal deformity (ASD) surgery by examining health-related quality of life (HRQOL) measures over time via an integrated health state analysis (IHS).
A retrospective review of a multicenter, prospective ASD database was conducted. Complication number, type, and need for reoperation (REOP) or not (NOREOP) were recorded. Patients were stratified as having no complication (NOCOMP), any complication (COMP), only minor complications (MINOR) and any major complications (MAJOR). HRQOL measures included Oswestry Disability Index (ODI), Short Form-36 (SF-36), and Scoliosis Research Society-22 (SRS22) at baseline, 6 weeks, 1 and 2 years postoperatively. All HRQOL scores were normalized to each patient's baseline scores and an IHS was then calculated.
149 patients were included. COMP, MINOR, and MAJOR had significantly lower normalized SRS mental scores at 1 and 2 years than NOCOMP (p < 0.05). REOP had significantly worse normalized 1 and 2 year mental component score (MCS), SRS mental, and total score than NOCOMP (p < 0.05). COMP, MINOR, and MAJOR all had significantly lower SRS mental IHSs than NOCOMP (p < 0.05). REOP had significantly lower IHSs for MCS and SRS satisfaction than NOREOP (p < 0.05). REOP had a significantly lower MCS and SRS mental IHS than NOCOMP (p < 0.05).
An IHS analysis suggests there was a significantly protracted mental recovery phase associated with patients that had at least one complication, as well as either a minor and major complication. The addition of a reoperation also adversely affected the mental recovery as well as overall satisfaction.
通过综合健康状态分析(IHS),随时间检查健康相关生活质量(HRQOL)指标,以确定并发症和再次手术对成人脊柱畸形(ASD)手术后恢复过程的影响。
对一个多中心前瞻性ASD数据库进行回顾性研究。记录并发症数量、类型以及是否需要再次手术(REOP)或无需再次手术(NOREOP)。患者被分层为无并发症(NOCOMP)、有任何并发症(COMP)、仅有轻微并发症(MINOR)和有任何严重并发症(MAJOR)。HRQOL指标包括术前、术后6周、1年和2年时的Oswestry功能障碍指数(ODI)、简明健康调查问卷36项(SF - 36)以及脊柱侧凸研究学会22项问卷(SRS22)。所有HRQOL评分均根据每位患者的基线评分进行标准化,然后计算IHS。
纳入149例患者。COMP、MINOR和MAJOR组在术后1年和2年时的标准化SRS心理评分显著低于NOCOMP组(p < 0.05)。REOP组术后1年和2年的标准化心理成分评分(MCS)、SRS心理评分和总分显著低于NOCOMP组(p < 0.05)。COMP、MINOR和MAJOR组的SRS心理IHS均显著低于NOCOMP组(p < 0.05)。REOP组的MCS和SRS满意度IHS显著低于NOREOP组(p < 0.05)。REOP组的MCS和SRS心理IHS显著低于NOCOMP组(p < 0.05)。
IHS分析表明,至少有一项并发症(无论是轻微还是严重并发症)的患者,其心理恢复阶段明显延长。再次手术的实施也对心理恢复以及总体满意度产生了不利影响。