继发性甲状旁腺功能亢进中的颌面部棕色瘤：一例报告及文献复习
Maxillofacial brown tumors in secondary hyperparathyroidism: A case report and literature review.
作者信息
Jafari-Pozve Nasim, Ataie-Khorasgani Masoud, Jafari-Pozve Shahram, Ataie-Khorasgani Mahnaz
机构信息
Dental Implants Research Center, Department of Oral and Maxillofacial Radiology, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran ; Students' Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2014 Nov;19(11):1099-102.
Parathyroid glands produce parathyroid hormone (PTH). PTH has a main role in bone formation. Hyperparathyroidism (HPT) is explained as primary, secondary and tertiary types defined as overproduction of PTH. The brown tumor or osteitis fibrosa cystica is a benign bone lesion that is caused by HPT. This complication has been decreased by diagnosis and successful treatment of secondary hyperparathyroidism. Pelvis, ribs, clavicle, mandible and the extremities are most commonly affected bone in brown tumor, whereas maxillary involvement is rare. The present article report a 29-year-old man with chief complaints of bone pain, swelling cheeks and teeth displacement with secondary HPT. Parathyroidectomy was done due to bone disorder. It is important for dentists and endocrinologists to understand maxillofacial manifestation of secondary HPT to prevent its complication.
甲状旁腺分泌甲状旁腺激素（PTH）。PTH在骨形成中起主要作用。甲状旁腺功能亢进症（HPT）分为原发性、继发性和三发性，其定义为PTH分泌过多。棕色瘤或纤维囊性骨炎是一种由HPT引起的良性骨病变。通过对继发性甲状旁腺功能亢进症的诊断和成功治疗，这种并发症已有所减少。棕色瘤最常累及骨盆、肋骨、锁骨、下颌骨和四肢，而上颌受累罕见。本文报道了一名29岁男性，主要症状为骨痛、脸颊肿胀和牙齿移位，患有继发性HPT。因骨病进行了甲状旁腺切除术。牙医和内分泌学家了解继发性HPT的颌面表现以预防其并发症很重要。
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