家鸡（原鸡）出血期间肾血流动力学与精氨酸加压催产素和中催产素血浆水平之间的关系。

Relationships between renal hemodynamics and plasma levels of arginine vasotocin and mesotocin during hemorrhage in the domestic fowl (Gallus domesticus).

Bottje W G, Holmes K R, Neldon H L, Koike T K

Department of Animal Sciences, University of Arkansas, Fayetteville 72701.

Comp Biochem Physiol A Comp Physiol. 1989;92(3):423-7. doi: 10.1016/0300-9629(89)90586-0.

Abstract

Renal tissue blood flow (renal perfusion) and plasma levels of arginine vasotocin (AVT) and mesotocin (MT) were measured in anesthetized chickens before and during hemorrhage. 2. Renal perfusion did not decrease (P less than 0.05) until nearly 50% of the blood volume had been removed. The decrease in renal perfusion was not related to arterial blood pressure but was concomitant with an increase (P less than 0.05) in plasma AVT levels. 3. Renal perfusion during hemorrhage was positively correlated with plasma MT levels by the regression equation: renal perfusion = 0.091 (MT)-1.1459 which was highly significant (P less than 0.001, r2 = 0.95). 4. The results of this study suggest that MT as well as AVT may participate in regulating blood flow in the avian kidney.

摘要

在麻醉的鸡出血前及出血过程中，测量了肾组织血流量（肾灌注）以及精氨酸血管加压催产素（AVT）和中催产素（MT）的血浆水平。2. 直到将近50%的血容量被移除时，肾灌注才下降（P<0.05）。肾灌注的下降与动脉血压无关，而是与血浆AVT水平的升高（P<0.05）同时出现。3. 出血期间的肾灌注与血浆MT水平通过回归方程呈正相关：肾灌注=0.091（MT）-1.1459，这具有高度显著性（P<0.001，r2=0.95）。4. 本研究结果表明，MT以及AVT可能参与调节鸟类肾脏的血流。