• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

波吲洛尔:对轻至中度原发性高血压患者血压、肾功能、血浆肾素活性及血浆醛固酮的长期影响

Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension.

作者信息

Shohat J, Modan M, Rosenfeld J B

机构信息

Nephrology Unit, Beilinson Medical Center, Petah Tikva, Israel.

出版信息

Fundam Clin Pharmacol. 1989;3(1):53-8. doi: 10.1111/j.1472-8206.1989.tb00030.x.

DOI:10.1111/j.1472-8206.1989.tb00030.x
PMID:2565862
Abstract

Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged.

摘要

波吲洛尔以每日1至4毫克的单次剂量给予高血压患者。在86.7%的患者中,在治疗的前4周内舒张压就降低了10毫米汞柱或更多,或降至90毫米汞柱以下。菊粉清除率下降了10%;对氨基马尿酸和肌酐清除率、血尿素氮和血清肌酐均未改变。

相似文献

1
Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension.波吲洛尔:对轻至中度原发性高血压患者血压、肾功能、血浆肾素活性及血浆醛固酮的长期影响
Fundam Clin Pharmacol. 1989;3(1):53-8. doi: 10.1111/j.1472-8206.1989.tb00030.x.
2
Effects of a new long-acting beta-blocker bopindolol (LT 31-200) on blood pressure, plasma catecholamines, renin and cholesterol in patients with arterial hypertension.新型长效β受体阻滞剂波吲洛尔(LT 31 - 200)对动脉高血压患者血压、血浆儿茶酚胺、肾素及胆固醇的影响
Eur J Clin Pharmacol. 1982;22(6):491-3. doi: 10.1007/BF00609620.
3
Effects of bopindolol on renal function.波吲洛尔对肾功能的影响。
J Cardiovasc Pharmacol. 1986;8 Suppl 6:S45-50. doi: 10.1097/00005344-198608006-00011.
4
Acute and long-term antihypertensive effect of bopindolol--a nonselective beta-adrenergic blocker with ISA.波吲洛尔(一种具有内在拟交感活性的非选择性β肾上腺素能阻滞剂)的急性和长期降压作用
Eur J Clin Pharmacol. 1985;29(3):281-5. doi: 10.1007/BF00544081.
5
Antihypertensive effect of bopindolol: a multi-centre study.波吲洛尔的降压作用:一项多中心研究。
J Hum Hypertens. 1990 Aug;4(4):458-60.
6
Dose-finding study with bopindolol in arterial hypertension.
J Cardiovasc Pharmacol. 1986;8 Suppl 6:S25-9. doi: 10.1097/00005344-198608006-00006.
7
Double-blind comparison of once-daily bopindolol, pindolol and atenolol in essential hypertension.原发性高血压患者中每日一次服用波吲洛尔、吲哚洛尔和阿替洛尔的双盲比较。
Eur J Clin Pharmacol. 1984;27(5):529-34. doi: 10.1007/BF00556887.
8
[The antihypertensive efficacy and tolerance of bopindolol (LT 31-200) in hypertensive patients].
Rev Med Univ Navarra. 1990 Apr-Jun;34(2):90-4.
9
Withdrawal of the long-acting beta blocker bopindolol is not associated with beta-adrenoceptor supersensitivity.长效β受体阻滞剂波吲洛尔的撤药与β肾上腺素能受体超敏反应无关。
J Cardiovasc Pharmacol. 1986;8 Suppl 6:S64-9. doi: 10.1097/00005344-198608006-00015.
10
Antihypertensive treatment with bopindolol alone or combined with a diuretic in general practice.
J Cardiovasc Pharmacol. 1986;8 Suppl 6:S80-7. doi: 10.1097/00005344-198608006-00019.

引用本文的文献

1
Bopindolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.波吲洛尔:其药效学、药代动力学特性及治疗效果综述
Drugs. 1991 Jan;41(1):130-49. doi: 10.2165/00003495-199141010-00010.