Centre de Recherche en Odontologie Clinique EA 4847, CHU Clermont-Ferrand, France.
Med Princ Pract. 2015;24(3):216-21. doi: 10.1159/000371709. Epub 2015 Feb 6.
The aim of this systematic review was to evaluate the in vivo scientific evidence of the ability of resin infiltration (RI) to arrest non-cavitated caries lesions.
The PubMed database was searched for randomized controlled trials that evaluated the in vivo effect of RI versus placebo or other preventive treatment on the progression of caries lesions. The keywords used were 'resin infiltration, dental caries', 'resin infiltration, carious lesions', 'resin infiltration, caries lesions', 'caries infiltration' and 'Icon DMG' with the 'clinical trial' filter activated. Among the 14 articles originally identified with these keywords, only 4 (related to 3 different in vivo studies) were included for this review.
All 4 articles reported on proximal caries lesions. One study had been conducted on 48 high-caries-risk children while the other 3 (n = 22, 22 and 39, respectively) concerned moderate- and low-caries-risk adolescents and adults. The quality of the studies was assessed to be high with respect to randomization, split-mouth design and blinding. All the included studies showed significant differences in caries progression between test and control/placebo groups, indicating that RI may inhibit the carious process.
This systematic review revealed that RI appeared to be an effective method to arrest the progression of non-cavitated caries lesions. Additional, long-term studies are required.
本系统评价旨在评估树脂渗透(RI)在阻止非龋性龋损进展方面的体内科学证据。
在 PubMed 数据库中搜索了评估 RI 与安慰剂或其他预防治疗对龋损进展影响的随机对照试验。使用的关键词是“resin infiltration, dental caries”、“resin infiltration, carious lesions”、“resin infiltration, caries lesions”、“caries infiltration”和“Icon DMG”,并激活“临床试验”过滤器。在最初使用这些关键词识别出的 14 篇文章中,只有 4 篇(与 3 项不同的体内研究相关)被纳入本综述。
所有 4 篇文章均报道了近中龋损。一项研究在 48 名高龋风险儿童中进行,而另外 3 项研究(n = 22、22 和 39,分别)涉及中龋和低龋风险的青少年和成年人。这些研究的质量被评估为随机化、分口设计和盲法高。所有纳入的研究都显示了试验组和对照组/安慰剂组之间龋病进展的显著差异,表明 RI 可能抑制龋病进程。
本系统评价显示,RI 似乎是阻止非龋性龋损进展的有效方法。需要进一步进行长期研究。