在补骨脂素光化学疗法（PUVA）治疗银屑病期间，骨髓发育异常转化为急性髓系白血病。
Transformation of myelodysplasia to acute myeloid leukaemia during psoralen photochemotherapy (PUVA) treatment of psoriasis.
作者信息
Sheehan-Dare R A, Cotterill J A, Barnard D L
机构信息
Department of Dermatology, General Infirmary, Leeds, England.
出版信息
Acta Derm Venereol. 1989;69(3):262-4.
PMID:2566239
Abstract
A patient with stable chronic myelomonocytic leukaemia was treated with 8-methoxypsoralen photochemotherapy (PUVA) for erythrodermic psoriasis. After 4 months, transformation to acute myeloid leukaemia (AML) occurred. We would suggest caution when considering PUVA therapy in patients with pre-leukaemic disorders.
摘要
一名患有稳定期慢性粒单核细胞白血病的患者接受了8-甲氧基补骨脂素光化学疗法（PUVA）治疗红皮病型银屑病。4个月后，发生了向急性髓系白血病（AML）的转化。我们建议在考虑对患有白血病前期疾病的患者进行PUVA治疗时要谨慎。
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