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[银屑病和副银屑病的放射治疗]

[Radiation therapy of psoriasis and parapsoriasis].

作者信息

Wiskemann A

出版信息

Z Hautkr. 1982 Sep 15;57(18):1317-24.

PMID:7148059
Abstract

Selective UV-Phototherapy with lambda 300-320 nm (SUP) as well as oral photochemotherapy with 8-methoxy-psoralene plus UVA-radiation (PUVA intern) are very effective in clearing the lesions of th generalized psoriasis and those of the chronic forms of parapsoriasis. Being treated with 4 suberythemal doses per week psoriasis patients are free or nearly free of symptoms after averaging 6.3 weeks of SUP-therapy or after 5.3 weeks of PUVA orally. The PUVA-therapy is mainly indicated in pustular, inverse and erythrodermic psoriasis as well as in parapsoriasis in plaques and variegata. In all other forms of psoriasis and in pityriasis lichenoides chronica, we prefer the SUP-therapy because of less acute or chronic side effects, and because of its better practicability. X-rays are indicated in psoriasis of nails, grenz-rays in superficial psoriatic lesions of the face, the armpits, the genitals and the anal region.

摘要

采用波长300 - 320纳米的选择性紫外线光疗(SUP)以及8 - 甲氧基补骨脂素加UVA辐射的口服光化学疗法(PUVA intern)在清除泛发性银屑病和慢性点滴状副银屑病的皮损方面非常有效。接受每周4次亚红斑剂量治疗的银屑病患者,在平均接受6.3周的SUP治疗或5.3周的口服PUVA治疗后,症状可完全消失或几乎完全消失。PUVA疗法主要适用于脓疱型、反向型和红皮病型银屑病以及斑块状和杂色型副银屑病。在所有其他类型的银屑病和慢性苔藓样糠疹中,我们更倾向于SUP疗法,因为它的急慢性副作用较少,实用性更强。X射线适用于甲银屑病,境界线照射适用于面部、腋窝、生殖器和肛门区域的浅表银屑病皮损。

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