中国日间手术不同麻醉方案的成本效益

Cost-effectiveness of different regimens of anesthesia for day surgery in China.

作者信息

Shen Liang, Luo Yan, Lu Zhijun, Hu Xiang, Ding Wen, Yu Buwei

机构信息

Department of Anesthesiology, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine Shanghai 200020, China.

Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200025, China.

出版信息

Int J Clin Exp Med. 2014 Dec 15;7(12):5744-50. eCollection 2014.

PMID:25664101

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4307548/

Abstract

OBJECTIVES

To compare the cost-effectiveness of inhalation of sevoflurane, target-controlled infusion (TCI) of propofol, intravenous (IV) propofol for induction-inhalation of sevoflurane, and IV propofol for induction-inhalation of desoflurane for anesthesia maintenance in day surgery.

METHODS

240 patients, scheduled for elective day surgery, were randomly divided into 4 groups (n = 60 each): inhalation of sevoflurane anesthesia group (group S); TCI of propofol anesthesia (group P); and intravenous propofol for induction of anesthesia-inhalation of sevoflurane for maintenance of anesthesia group (group PS); and intravenous propofol for induction of anesthesia-inhalation of desoflurane for maintenance of anesthesia group (group PD).

RESULTS

Group S was associated with less time to loss of consciousness, as well as the other three groups were associated with less time to recovery (P < 0.05). Group P was associated with a higher anesthetic agents cost than other 3 groups (P < 0.05), and group S was associated with a higher anesthetic agents costs than group PS and PD (P < 0.05).

CONCLUSION

Induction with intravenous injection of propofol and maintenance with inhalation of desoflurane is the most cost-effective method of anesthesia for day surgery.

摘要

目的

比较七氟醚吸入、丙泊酚靶控输注（TCI）、静脉注射丙泊酚诱导-七氟醚吸入以及静脉注射丙泊酚诱导-地氟醚吸入用于日间手术麻醉维持的成本效益。

方法

240例择期日间手术患者随机分为4组（每组n = 60）：七氟醚吸入麻醉组（S组）；丙泊酚TCI麻醉组（P组）；静脉注射丙泊酚诱导-七氟醚吸入维持麻醉组（PS组）；静脉注射丙泊酚诱导-地氟醚吸入维持麻醉组（PD组）。

结果

S组意识消失时间较短，其他三组苏醒时间较短（P < 0.05）。P组麻醉药费用高于其他3组（P < 0.05），S组麻醉药费用高于PS组和PD组（P < 0.05）。

结论

静脉注射丙泊酚诱导、地氟醚吸入维持是日间手术最具成本效益的麻醉方法。

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