Jamshidi Ahmad-Reza, Tehrani Banihashemi Arash, Roknsharifi Shima, Akhlaghi Masoumeh, Salimzadeh Ahmad, Davatchi Fereydoun
1. MD, Professor of Rheumatology, Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
2. MD, MPH, School of Public Health, Department of Epidemiology, Iran University of Medical Sciences & Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2014 Sep 14;28:93. eCollection 2014.
To estimate the prevalence and characteristics of Rheumatoid Arthritis (RA) in an urban area of Tehran.
A total of 50 clusters were randomly selected in Tehran and 10291 subjects completed the COPCORD Core Questionnaire during 2004 and 2005. Patients with rheumatic complaints were examined and diagnosed by subspecialty fellows in rheumatology. Laboratory and radiology tests were also performed if required.
A total of 35 subjects (5 men and 30 women) were diagnosed with RA, with a prevalence of 0.33% (95% CI: 0.22-0.46). Our results demonstrated that RA was six times more common in women than men. The mean age (± SD) of patients was 52.3 (± 17.6) years. Morning stiffness > 1 hour was reported in 37.1% of patients. Rheumatic signs were commonly found in wrist (60%), knee (60%), metacarpophalangeal (48.6%) and proximal interphalangeals of hand (40%). Approximately 46% of patients had difficulty carrying out daily activities.
According to our study, the prevalence of RA in Iran seems to be lower than western countries. However, the prevalence of RA in Iran seems to be approximately in the middle point comparing the APLAR region (from 0.7% in Australia (rural) to 0.12% in Thailand).
评估德黑兰市区类风湿关节炎（RA）的患病率及特征。
在德黑兰随机选取50个群组，10291名受试者在2004年至2005年期间完成了COPCORD核心问卷。有风湿症状的患者由风湿病专科研究员进行检查和诊断。必要时还进行了实验室和放射学检查。
共35名受试者（5名男性和30名女性）被诊断为RA，患病率为0.33%（95%可信区间：0.22 - 0.46）。我们的结果表明，女性患RA的几率是男性的6倍。患者的平均年龄（±标准差）为52.3（±17.6）岁。37.1%的患者报告晨僵超过1小时。风湿体征常见于手腕（60%）、膝盖（60%）、掌指关节（48.6%）和手部近端指间关节（40%）。约46%的患者在进行日常活动时有困难。
根据我们的研究，伊朗RA的患病率似乎低于西方国家。然而，与亚太风湿病学联盟（APLAR）地区相比（从澳大利亚农村地区的0.7%到泰国的0.12%），伊朗RA的患病率似乎大致处于中间水平。
