Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina 27599.
Annu Rev Physiol. 2015;77:1-11. doi: 10.1146/annurev-physiol-021014-071806.
Professor Oliver Smithies is the Weatherspoon Eminent Distinguished Professor of Pathology and Laboratory Medicine at the University of North Carolina, Chapel Hill. Along with Mario Capecchi and Martin Evans, Oliver was awarded the Nobel Prize in Medicine in Physiology or Medicine in 2007 for his contributions to the development of gene targeting using homologous recombination in embryonic stem cells. This technique has had an immense impact on biomedical research over the past two decades. Professor Smithies has had a long and distinguished career as a researcher and mentor. Here, he provides an entertaining and enlightening discussion of his life in science.
奥利弗·史密斯教授是北卡罗来纳大学教堂山分校病理学和实验医学的 Weatherspoon 杰出杰出教授。奥利弗与马里奥·卡佩基和马丁·埃文斯一起，因其在胚胎干细胞同源重组基因靶向技术方面的贡献而获得 2007 年诺贝尔生理学或医学奖。这项技术在过去二十年对生物医学研究产生了巨大影响。史密斯教授作为一名研究人员和导师，有着长期而杰出的职业生涯。在这里，他对自己的科学人生进行了一场有趣而富有启发性的讨论。
