Miczek K A, Haney M, Tidey J, Vatne T, Weerts E, DeBold J F
Department of Psychology, Tufts University, Medford, MA 02155.
Psychopharmacology (Berl). 1989;97(2):149-51. doi: 10.1007/BF00442237.
Social and agonistic interactions are composed of a range of species-typical acts, postures, displays and other communicative signals that follow characteristic patterns. Descriptive and analytic methods permit an assessment of the temporal and sequential features of highly probable patterns of agonistic interactions. Analysis of the intervals that separate consecutive attacks by a resident mouse or rat toward an intruder identifies bursts or epochs of attacks. Amphetamine (1.25, 2.5 mg/kg), but not diazepam or alcohol, alters the burst pattern of attack behavior. Higher doses of alcohol, but not diazepam, in either resident male rats or in lactating rats confronting an intruder, reduce the sequences of aggressive acts and postures with high transition probabilities as identified by lag sequential analysis. These results suggest that temporal and sequential patterning mechanisms may be differentially altered by amphetamine- and alcohol-type substances. These neural for many types of behavior.
社会互动和争斗互动由一系列具有物种典型特征的行为、姿势、展示及其他遵循特定模式的交流信号组成。描述性和分析性方法能够对争斗互动的高度可能模式的时间和顺序特征进行评估。对一只居主导地位的小鼠或大鼠对入侵者连续攻击之间的间隔进行分析，可识别出攻击的爆发或时段。苯丙胺（1.25、2.5毫克/千克）而非地西泮或酒精会改变攻击行为的爆发模式。在居主导地位的雄性大鼠或面对入侵者的哺乳期大鼠中，高剂量酒精而非地西泮，会减少通过滞后序列分析确定的具有高转换概率的攻击行为和姿势序列。这些结果表明，时间和顺序模式形成机制可能会被苯丙胺类和酒精类物质以不同方式改变。这些神经机制对多种行为类型都很重要。
