Wratten Cariad J E, Tetsworth Kevin, Hohmann Erik
School of Medicine, University of Queensland, Brisbane, Australia.
Royal Brisbane and Women's Hospital, Brisbane, Australia.
Arthroscopy. 2015 Jun;31(6):1117-22. doi: 10.1016/j.arthro.2014.12.014. Epub 2015 Feb 7.
The purpose of this study was to evaluate between-gender differences in 3-dimensional femoral notch volume in anterior cruciate ligament (ACL)-deficient patients compared with a matched control group of ACL-intact patients.
Magnetic resonance images from 90 ACL-deficient patients (45 male and 45 female patients) aged 16 to 50 years were identified from our departmental database and then compared with a matched control group of ACL-intact patients. The 3-dimensional femoral notch volume on each magnetic resonance imaging study was measured using software-specific tools. One-way analysis of variance was used to compare notch volume between the ACL-deficient and ACL-intact groups and between the 2 genders. The relations between height, weight, body mass index, and notch volume for each group and within the male and female cohorts were established using Pearson product moment correlations.
The mean femoral notch volume in the female ACL-deficient group was 3.1 ± 0.70 cm(3) (95% confidence interval [CI], ± 0.2 cm(3)) compared with 3.6 ± 0.7 cm(3) (95% CI, ± 0.2 cm(3)) in the female control group. The mean femoral notch volume in the male ACL-deficient group was 4.5 ± 1.1 cm(3) (95% CI, ± 0.3 cm(3)) compared with 5.3 ± 1.2 cm(3) (95% CI, ± 0.4 cm(3)) in the male control group. There were significant differences between the male ACL-deficient and ACL-intact groups (P = .02), between the female ACL-deficient and ACL-intact groups (P = .0002), between the male and female ACL-deficient groups (P < .0001), and between the male and female ACL-intact groups (P < .0001). There were nonsignificant relations (r = 0.01 to 0.37) between height, weight, body mass index, and notch volume between groups and within the male and female cohorts.
These results show a decreased femoral notch volume as measured on 3-dimensional magnetic resonance imaging in ACL-deficient patients. There were significant differences in femoral notch volume between the male and female cohorts, as well as between ACL-deficient and ACL-intact patients of both genders. In the female cohort there was a 14% reduction in volume between the ACL-deficient and ACL-intact patients; in the male cohort there was a 15% corresponding reduction in volume. There was a 31% reduction in volume between genders in ACL-deficient patients, with female patients having a smaller volume than male patients. There was a corresponding 32% reduction in volume between genders in ACL-intact patients.
Level III, case-control study.
本研究旨在评估前交叉韧带（ACL）损伤患者与ACL完整的匹配对照组患者之间股骨髁间窝三维容积的性别差异。
从我们科室的数据库中识别出90例年龄在16至50岁之间的ACL损伤患者（45例男性和45例女性患者）的磁共振成像，然后与ACL完整的匹配对照组患者进行比较。使用软件特定工具测量每次磁共振成像研究中的股骨髁间窝三维容积。采用单因素方差分析比较ACL损伤组与ACL完整组之间以及两性之间的髁间窝容积。使用Pearson积矩相关性建立每组以及男性和女性队列中身高、体重、体重指数与髁间窝容积之间的关系。
女性ACL损伤组的平均股骨髁间窝容积为3.1±0.70 cm³（95%置信区间[CI]，±0.2 cm³），而女性对照组为3.6±0.7 cm³（95% CI，±0.2 cm³）。男性ACL损伤组的平均股骨髁间窝容积为4.5±1.1 cm³（95% CI，±0.3 cm³），而男性对照组为5.3±1.2 cm³（95% CI，±0.4 cm³）。男性ACL损伤组与ACL完整组之间（P = 0.02）、女性ACL损伤组与ACL完整组之间（P = 0.0002）、男性和女性ACL损伤组之间（P < 0.0001）以及男性和女性ACL完整组之间（P < 0.0001）存在显著差异。组间以及男性和女性队列中身高、体重、体重指数与髁间窝容积之间存在不显著的关系（r = 0.01至0.37）。
这些结果表明，ACL损伤患者在三维磁共振成像上测量的股骨髁间窝容积减小。男性和女性队列之间以及两性的ACL损伤患者与ACL完整患者之间的股骨髁间窝容积存在显著差异。在女性队列中，ACL损伤患者与ACL完整患者之间的容积减少了14%；在男性队列中，相应的容积减少了15%。ACL损伤患者中两性之间的容积减少了31%，女性患者的容积小于男性患者。ACL完整患者中两性之间的容积相应减少了32%。
III级，病例对照研究。
