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Synthesis of 3-[2-(2,3-dihydro-5-phenyl-4-substituted-3H-1,2,4- triazole-3-thione-2-yl)-acetylamino]-2-methyl-4(3H)-quinazolinones and their pharmacological activities.

作者信息

Büyüktimkin S, Büyüktimkin N, Ozdemir O, Rollas S

出版信息

Arch Pharm (Weinheim). 1989 Jan;322(1):49-51. doi: 10.1002/ardp.19893220112.

DOI:10.1002/ardp.19893220112
PMID:2567155
Abstract

Some 2-methyl-3-triazole-substituted-4(3H)-quinazolinones 3a-f were prepared and tested for their H1- and H2-antihistaminic activities. In addition these compounds are central nervous system depressants and anticonvulsants. 3e shows highly significant decrease of locomotor activity.

摘要

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