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结节性多动脉炎和变应性肉芽肿性血管炎的症状性泌尿生殖系统表现:165例患者中8例的分析

Symptomatic urogenital manifestations of polyarteritis nodosa and Churg-Strauss angiitis: analysis of 8 of 165 patients.

作者信息

Azar N, Guillevin L, Huong Du L T, Herreman G, Meyrier A, Godeau P

机构信息

Department of Internal Medicine, Hôpital Avicenne, Bobigny, France.

出版信息

J Urol. 1989 Jul;142(1):136-8. doi: 10.1016/s0022-5347(17)38686-x.

Abstract

To establish the clinical features and evolution of ureteral and testicular manifestations of polyarteritis nodosa, 8 cases among a group of 165 patients were reviewed. Urogenital manifestations are rare and were related to hepatitis B virus markers in 5 of the 8 patients. Malignant hypertension was present in 6 of 8 patients and renal insufficiency related to renal infarctions was noted in 5. Prognosis is good and regression generally is obtained with steroid therapy or with plasma exchange and vidarabine when polyarteritis is related to hepatitis B virus. In some cases ureteral stenosis may require an operation in association with steroids and/or immunosuppressive treatments.

摘要

为明确结节性多动脉炎输尿管和睾丸表现的临床特征及演变过程,我们回顾了165例患者中的8例。泌尿生殖系统表现罕见,8例患者中有5例与乙肝病毒标志物有关。8例患者中有6例出现恶性高血压,5例出现与肾梗死相关的肾功能不全。当结节性多动脉炎与乙肝病毒相关时,预后良好,一般通过类固醇治疗或血浆置换及阿糖腺苷可实现病情缓解。在某些情况下,输尿管狭窄可能需要联合类固醇和/或免疫抑制治疗进行手术。

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