• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

槟榔及其在口腔黏膜下纤维化中的作用。

Areca nut and its role in oral submucous fibrosis.

作者信息

Prabhu Rachana V, Prabhu Vishnudas, Chatra Laxmikanth, Shenai Prashant, Suvarna Nithin, Dandekeri Savita

机构信息

Reader. Department of Oral Medicine and Radiology, Yenepoya Dental College, Yenepoya University, Mangalore, Karnataka, India.

Professor. Department of Oral and Maxillofacial Pathology, Yenepoya Detal College and Hospital. Yenepoya University, Mangalore, Karnataka, India.

出版信息

J Clin Exp Dent. 2014 Dec 1;6(5):e569-75. doi: 10.4317/jced.51318. eCollection 2014 Dec.

DOI:10.4317/jced.51318
PMID:25674328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4312688/
Abstract

Areca nut, commonly called as betel nut or supari, is a fruit of areca catechu palm tree, which is native of South Asia and Pacific Islands. The seed or endosperm is consumed fresh, boiled or after sun drying or curing. Chewing areca nut is thought to have central nervous system stimulating effect and along with this it is known to have salivary stimulating and digestive properties. According to the traditional Ayurvedic medicine, chewing areca nut and betel leaf is a good remedy against halitosis. It is also used for its deworming property. Along with these beneficial effects of areca nut one of its most harmful effects on the human body in general and oral cavity in particular is the development of potentially malignant disorder called Oral Submucous Fibrosis. The present paper discusses in detail the effects of the components of areca nut on pathogenesis of Oral Submucous Fibrosis. Key words:Areca nut, oral submucous fibrosis, potentially malignant disorder, supari.

摘要

槟榔,通常被称为槟榔果或蒌叶,是槟榔树的果实,原产于南亚和太平洋岛屿。种子或胚乳可新鲜食用、煮熟后食用,或经过晒干或加工后食用。嚼槟榔被认为具有刺激中枢神经系统的作用,此外,它还具有刺激唾液分泌和助消化的特性。根据传统的阿育吠陀医学,嚼槟榔和蒌叶是治疗口臭的良方。它还因其驱虫特性而被使用。除了槟榔的这些有益作用外,它对人体尤其是口腔最有害的影响之一是发展为一种潜在的恶性疾病,称为口腔黏膜下纤维化。本文详细讨论了槟榔成分对口腔黏膜下纤维化发病机制的影响。关键词:槟榔、口腔黏膜下纤维化、潜在恶性疾病、蒌叶

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/cf0394ecc5a0/jced-6-e569-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/31a6b9507f8a/jced-6-e569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/a5e2a0a06e9e/jced-6-e569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/ec118385e193/jced-6-e569-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/cf0394ecc5a0/jced-6-e569-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/31a6b9507f8a/jced-6-e569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/a5e2a0a06e9e/jced-6-e569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/ec118385e193/jced-6-e569-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6505/4312688/cf0394ecc5a0/jced-6-e569-g004.jpg

相似文献

1
Areca nut and its role in oral submucous fibrosis.槟榔及其在口腔黏膜下纤维化中的作用。
J Clin Exp Dent. 2014 Dec 1;6(5):e569-75. doi: 10.4317/jced.51318. eCollection 2014 Dec.
2
Why only areca nut chewing cannot cause oral submucous fibrosis?为什么仅仅咀嚼槟榔不能导致口腔黏膜下纤维性变?
Med Hypotheses. 2013 Jul;81(1):47-9. doi: 10.1016/j.mehy.2013.02.025. Epub 2013 Apr 18.
3
Areca Nut槟榔
4
Oral submucous fibrosis: A global challenge. Rising incidence, risk factors, management, and research priorities.口腔黏膜下纤维性变:全球性挑战。发病率上升、危险因素、管理和研究重点。
Periodontol 2000. 2019 Jun;80(1):200-212. doi: 10.1111/prd.12277.
5
Are There Betel Quid Mixtures Less Harmful than Others? A Scoping Review of the Association between Different Betel Quid Ingredients and the Risk of Oral Submucous Fibrosis.有没有比其他混合物危害更小的槟榔混合物?不同槟榔成分与口腔黏膜下纤维性变风险之间关联的范围综述。
Biomolecules. 2022 May 2;12(5):664. doi: 10.3390/biom12050664.
6
Estimation and Comparison of Copper Content in Raw Areca Nuts and Commercial Areca Nut Products: Implications in Increasing Prevalence of Oral Submucous Fibrosis (OSMF).生槟榔和商业槟榔制品中铜含量的估计与比较:对口腔黏膜下纤维化(OSMF)患病率上升的影响
J Clin Diagn Res. 2014 Jan;8(1):247-9. doi: 10.7860/JCDR/2014/8042.3932. Epub 2014 Jan 12.
7
Effect of copper-based fungicide (bordeaux mixture) spray on the total copper content of areca nut: Implications in increasing prevalence of oral submucous fibrosis.基于铜的杀菌剂(波尔多液)喷雾对槟榔总铜含量的影响:对口腔黏膜下纤维化患病率上升的影响
J Int Soc Prev Community Dent. 2015 Jul-Aug;5(4):283-9. doi: 10.4103/2231-0762.161755.
8
[Epidemiological investigation of chewing fresh or dried betel nut and oral mucosal disease].嚼食鲜槟榔或干槟榔与口腔黏膜病的流行病学调查
Hua Xi Kou Qiang Yi Xue Za Zhi. 2016 Aug 1;34(4):391-394. doi: 10.7518/hxkq.2016.04.014.
9
Changes in plasma steroids and cytokines levels in betel chewing patients in Taiwan.台湾嚼槟榔患者血浆类固醇和细胞因子水平的变化。
Steroids. 2016 Jul;111:134-138. doi: 10.1016/j.steroids.2016.03.011. Epub 2016 Mar 23.
10
Head and neck squamous cell carcinoma in chronic areca nut chewing Indian women: Case series and review of literature.慢性咀嚼槟榔的印度女性头颈部鳞状细胞癌:病例系列及文献综述
Indian J Med Paediatr Oncol. 2012 Jan;33(1):32-5. doi: 10.4103/0971-5851.96966.

引用本文的文献

1
An in-vitro exploration of the antifibrotic activity of Naringenin: A potential therapeutic agent for oral submucous fibrosis management.柚皮素抗纤维化活性的体外研究:一种用于口腔黏膜下纤维化治疗的潜在治疗剂。
J Oral Biol Craniofac Res. 2025 Jul-Aug;15(4):849-857. doi: 10.1016/j.jobcr.2025.06.006. Epub 2025 Jun 12.
2
Resveratrol inhibits arecoline-induced fibrotic properties of buccal mucosal fibroblasts via miR-200a activation.白藜芦醇通过激活miR-200a抑制槟榔碱诱导的颊黏膜成纤维细胞的纤维化特性。
J Dent Sci. 2024 Apr;19(2):1028-1035. doi: 10.1016/j.jds.2023.06.027. Epub 2023 Jul 8.
3
Prevalence of Oral Submucous Fibrosis With Other Oral Potentially Malignant Disorders: A Clinical Retrospective Study.

本文引用的文献

1
Orofacial manifestations of hematological disorders: anemia and hemostatic disorders.血液系统疾病的口腔面部表现:贫血和止血障碍。
Indian J Dent Res. 2011 May-Jun;22(3):454-61. doi: 10.4103/0970-9290.87070.
2
Early diagnosis of progressive systemic sclerosis (scleroderma) from a panoramic view: report of three cases.从全景角度早期诊断进行性系统性硬皮病(硬皮病):三例报告。
Dentomaxillofac Radiol. 2011 Oct;40(7):457-62. doi: 10.1259/dmfr/64340754.
3
Areca nut in pathogenesis of oral submucous fibrosis: revisited.槟榔在口腔黏膜下纤维化发病机制中的作用:再探讨
口腔黏膜下纤维化与其他口腔潜在恶性疾病的患病率:一项临床回顾性研究。
Cureus. 2023 Nov 29;15(11):e49642. doi: 10.7759/cureus.49642. eCollection 2023 Nov.
4
Expression of transforming growth factor-β in oral submucous fibrosis: A systematic review.转化生长因子-β在口腔黏膜下纤维化中的表达:一项系统评价。
J Oral Maxillofac Pathol. 2023 Apr-Jun;27(2):348-358. doi: 10.4103/jomfp.jomfp_536_22. Epub 2023 Jul 13.
5
Halitosis: etiology, prevention, and the role of microbiota.口臭:病因、预防及微生物群的作用。
Clin Oral Investig. 2023 Nov;27(11):6383-6393. doi: 10.1007/s00784-023-05292-9. Epub 2023 Oct 16.
6
Chemical Composition of Areca Nut and Its Adverse Effects on Human Health.槟榔的化学成分及其对人体健康的不良影响。
Cureus. 2023 Aug 19;15(8):e43739. doi: 10.7759/cureus.43739. eCollection 2023 Aug.
7
Arecoline aggravates acute ulcerative colitis in mice by affecting intestinal microbiota and serum metabolites.槟榔碱通过影响肠道微生物群和血清代谢物加重小鼠急性溃疡性结肠炎。
Front Immunol. 2023 Jul 10;14:1197922. doi: 10.3389/fimmu.2023.1197922. eCollection 2023.
8
The Immunolocalization of Mast Cells in the Pathology of Oral Submucous Fibrosis.肥大细胞在口腔黏膜下纤维化病理中的免疫定位
Cureus. 2023 Jun 6;15(6):e40069. doi: 10.7759/cureus.40069. eCollection 2023 Jun.
9
To Evaluate the Efficacy of Tissue Autofluorescence (Velscope) in the Visualization of Oral Premalignant and Malignant Lesions among High-Risk Population Aged 18 Years and Above in Haroli Block of Una, Himachal Pradesh.评估组织自体荧光(Velscope)在喜马偕尔邦乌纳哈罗利街区18岁及以上高危人群口腔癌前病变和恶性病变可视化中的疗效。
J Int Soc Prev Community Dent. 2022 Jun 29;12(3):365-375. doi: 10.4103/jispcd.JISPCD_22_22. eCollection 2022 May-Jun.
10
Are There Betel Quid Mixtures Less Harmful than Others? A Scoping Review of the Association between Different Betel Quid Ingredients and the Risk of Oral Submucous Fibrosis.有没有比其他混合物危害更小的槟榔混合物?不同槟榔成分与口腔黏膜下纤维性变风险之间关联的范围综述。
Biomolecules. 2022 May 2;12(5):664. doi: 10.3390/biom12050664.
Oral Maxillofac Surg. 2011 Mar;15(1):1-9. doi: 10.1007/s10006-010-0219-8.
4
Lichen sclerosus of the oral mucosa: a case report.口腔黏膜硬化性苔藓:一例报告。
Med Oral Patol Oral Cir Bucal. 2008 Jul 1;13(7):E403-6.
5
Epidemiological and etiological study of oral submucous fibrosis among gutkha chewers of Patna, Bihar, India.印度比哈尔邦巴特那嚼古特卡者口腔黏膜下纤维化的流行病学及病因学研究
J Indian Soc Pedod Prev Dent. 2006 Jun;24(2):84-9. doi: 10.4103/0970-4388.26022.
6
Molecular pathogenesis of oral submucous fibrosis--a collagen metabolic disorder.口腔黏膜下纤维化的分子发病机制——一种胶原代谢紊乱
J Oral Pathol Med. 2005 Jul;34(6):321-8. doi: 10.1111/j.1600-0714.2005.00325.x.
7
Epidemiology of betel quid usage.嚼食槟榔的流行病学。
Ann Acad Med Singap. 2004 Jul;33(4 Suppl):31-6.
8
Effects of arecoline, safrole, and nicotine on collagen phagocytosis by human buccal mucosal fibroblasts as a possible mechanism for oral submucous fibrosis in Taiwan.槟榔碱、黄樟素和尼古丁对人颊黏膜成纤维细胞胶原吞噬作用的影响——台湾口腔黏膜下纤维化的一种可能机制
J Oral Pathol Med. 2004 Oct;33(9):581-7. doi: 10.1111/j.1600-0714.2004.00229.x.
9
Augmented mRNA expression of tissue inhibitor of metalloproteinase-1 in buccal mucosal fibroblasts by arecoline and safrole as a possible pathogenesis for oral submucous fibrosis.槟榔碱和黄樟素可增强颊黏膜成纤维细胞中金属蛋白酶组织抑制剂-1的mRNA表达,这可能是口腔黏膜下纤维化的发病机制。
Oral Oncol. 2003 Oct;39(7):728-35. doi: 10.1016/s1368-8375(03)00101-5.
10
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis.槟榔碱对人颊黏膜成纤维细胞中环氧化酶-2表达的上调作用:在口腔黏膜下纤维化发病机制中的可能作用
J Oral Pathol Med. 2003 Mar;32(3):146-53. doi: 10.1034/j.1600-0714.2003.00004.x.