家畜的粪便病毒组
The fecal virome of domesticated animals.
作者信息
Mihalov-Kovács Eszter, Fehér Enikő, Martella Vito, Bányai Krisztián, Farkas Szilvia L
机构信息
Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Hungária krt. 21, Budapest, 1143 Hungary.
Department of Veterinary Public Health, University of Bari, S.p. per Casamassima km 3, 70010 Valenzano, Bari Italy.
出版信息
Virusdisease. 2014;25(2):150-7. doi: 10.1007/s13337-014-0192-1. Epub 2014 Feb 1.
Next-generation sequencing is a new research tool in our hands helping us to explore still unknown fields of human and veterinary virology. Metagenomic analysis has enabled the discovery of putative novel pathogens and the identification of the etiologic agents of several diseases, solving long-standing mysteries caused by divergent viruses. This approach has been used in several studies investigating fecal samples of livestock, and companion animal species, providing information on the diversity of animal fecal virome, helping the elucidation of the etiology of diarrheal disease in animals and identifying potential zoonotic and emerging viruses.
新一代测序技术是我们手中的一种新型研究工具，可帮助我们探索人类和兽医病毒学中仍未知的领域。宏基因组分析已促成了潜在新病原体的发现以及多种疾病病原体的鉴定，解开了由多种病毒引起的长期谜团。这种方法已用于多项研究家畜和伴侣动物粪便样本的研究中，提供了有关动物粪便病毒组多样性的信息，有助于阐明动物腹泻病的病因，并识别潜在的人畜共患病病毒和新出现的病毒。
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