Sarkar S, Sarkar S S, Dechert R E, Donn S M
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan Health System, Ann Arbor, MI, USA.
Research Volunteer, University of Michigan, Ann Arbor, MI, USA.
J Perinatol. 2015 Jul;35(7):490-2. doi: 10.1038/jp.2015.3. Epub 2015 Feb 12.
During therapeutic whole body cooling (WBC), the core temperature is usually monitored with an esophageal probe. Most infants receive mechanical ventilation while being cooled. As the temperature in the esophagus responds rapidly to changes in the ambient temperature, inhalation of warmed gas from ventilator may lead to overestimation of ventilated patients' actual temperature, causing automated cooling devices to overcool patients well below the desired set temperature targets. To determine if the esophageal temperature recordings during therapeutic WBC differ between ventilated and non-ventilated infants.
Twenty-two consecutively cooled infants had simultaneous esophageal and rectal temperatures recorded every 4 h during 72 h of WBC. Other clinical monitoring and treatment during hypothermia were provided under an established protocol.
Fourteen infants received mechanical ventilation throughout the duration of cooling. The remaining eight infants were initially ventilated but were extubated later and were not on ventilator between 32 and 72 h of WBC. The esophageal temperatures across every 4 h time points during the 32-72 h interval of WBC did not differ between the ventilated and non-ventilated infants. The magnitude (median, interquartile range) of the difference between esophageal and rectal temperatures was also similar between the two groups.
Warmed inhaled gas does not interfere with the esophageal temperature during WBC.
在治疗性全身降温(WBC)期间,通常使用食管探头监测核心温度。大多数婴儿在降温时接受机械通气。由于食管温度对环境温度变化反应迅速,从呼吸机吸入温热气体可能导致对接受机械通气患者的实际温度估计过高,从而使自动降温设备将患者过度冷却至远低于期望的设定温度目标。确定在治疗性WBC期间,接受机械通气和未接受机械通气的婴儿的食管温度记录是否存在差异。
22名接受连续降温的婴儿在WBC的72小时内每4小时同时记录食管温度和直肠温度。低温治疗期间的其他临床监测和治疗按照既定方案进行。
14名婴儿在整个降温期间接受机械通气。其余8名婴儿最初接受机械通气,但后来拔管,在WBC的32至72小时期间未使用呼吸机。在WBC的32至72小时间隔内,每4小时时间点的食管温度在接受机械通气和未接受机械通气的婴儿之间没有差异。两组之间食管温度与直肠温度差异的幅度(中位数,四分位间距)也相似。
在WBC期间,温热的吸入气体不会干扰食管温度。