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竹盐对C57BL/6小鼠的抗肥胖作用。

Antiobesity effects of bamboo salt in C57BL/6 mice.

作者信息

Ju Jaehyun, Song Jia-Le, Park Kun-Young

机构信息

Department of Food Science and Nutrition, Pusan National University, Busan, South Korea.

出版信息

J Med Food. 2015 Jun;18(6):706-10. doi: 10.1089/jmf.2014.3271. Epub 2015 Feb 12.

Abstract

Antiobesity effects of bamboo salt (BS) were evaluated compared with those of purified salt and solar salt by oral administration in a diet-induced obesity model using C57BL/6 mice. Compared with other salts, BS, especially nine times baked BS (BS-9×), significantly reduced body weight, food efficiency ratio, and weights of epididymal adipose tissue and liver in high-fat diet-fed mice. Furthermore, BS suppressed the expression of adipogenic factors, such as CCAAT/enhancer binding protein alpha (C/EBPα), peroxisome proliferator-activated receptor gamma (PPARγ), and sterol regulatory element-binding protein 1c (SREBP-1c). Therefore, BS may suppress obesity by downregulating adipogenesis.

摘要

在使用C57BL/6小鼠的饮食诱导肥胖模型中,通过口服给药,将竹盐(BS)与精制盐和日晒盐的抗肥胖作用进行了比较。与其他盐相比,竹盐,尤其是九烤竹盐(BS-9×),显著降低了高脂饮食喂养小鼠的体重、食物效率比以及附睾脂肪组织和肝脏的重量。此外,竹盐抑制了脂肪生成因子的表达,如CCAAT/增强子结合蛋白α(C/EBPα)、过氧化物酶体增殖物激活受体γ(PPARγ)和固醇调节元件结合蛋白1c(SREBP-1c)。因此,竹盐可能通过下调脂肪生成来抑制肥胖。

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