Porta Kelly, Rizzolo Denise
Kelly Porta is an assistant professor and academic coordinator in the PA program at Hofstra University in New York. She practices at the newborn nursery at Montefiore Medical Center and pediatric ICU at Jacobi Medical Center. Denise Rizzolo is an associate professor in the PA program at Seton Hall University in South Orange, N.J., an assistant clinical professor in the Pace completion program in New York City, and practices urgent care in Springfield, N.J. The authors have disclosed no potential conflicts of interest, financial or otherwise.
JAAPA. 2015 Mar;28(3):24-9. doi: 10.1097/01.JAA.0000460915.52391.70.
Despite advances in intrapartum antibiotic prophylaxis (IAP), group B streptococcal infection continues to be a predominant cause of early-onset disease in neonates. About 2% of neonates exposed to group B Streptococcus develop clinical manifestations including sepsis, pneumonia, and meningitis. Screening in late pregnancy reduces the incidence of early-onset sepsis by more than 80%. Clinicians must be able to identify the risk factors and clinical manifestations of group B streptococcal infection and to understand management and prevention guidelines.
尽管围产期抗生素预防（IAP）取得了进展，但B族链球菌感染仍然是新生儿早发型疾病的主要原因。约2%暴露于B族链球菌的新生儿会出现包括败血症、肺炎和脑膜炎在内的临床表现。孕晚期筛查可将早发型败血症的发病率降低80%以上。临床医生必须能够识别B族链球菌感染的危险因素和临床表现，并了解管理和预防指南。
