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用于手术模拟的脑组织表征与建模。

Characterisation and modelling of brain tissue for surgical simulation.

作者信息

Mendizabal A, Aguinaga I, Sánchez E

机构信息

Department of Applied Mechanics, CEIT, Donostia-San Sebastián, 20018, Spain.

出版信息

J Mech Behav Biomed Mater. 2015 May;45:1-10. doi: 10.1016/j.jmbbm.2015.01.016. Epub 2015 Jan 30.

DOI:10.1016/j.jmbbm.2015.01.016
PMID:25676499
Abstract

Interactive surgical simulators capable of providing a realistic visual and haptic feedback to users are a promising technology for medical training and surgery planification. However, modelling the physical behaviour of human organs and tissues for surgery simulation remains a challenge. On the one hand, this is due to the difficulty to characterise the physical properties of biological soft tissues. On the other hand, the challenge still remains in the computation time requirements of real-time simulation required in interactive systems. Real-time surgical simulation and medical training must employ a sufficiently accurate and simple model of soft tissues in order to provide a realistic haptic and visual response. This study attempts to characterise the brain tissue at similar conditions to those that take place on surgical procedures. With this aim, porcine brain tissue is characterised, as a surrogate of human brain, on a rotational rheometer at low strain rates and large strains. In order to model the brain tissue with an adequate level of accuracy and simplicity, linear elastic, hyperelastic and quasi-linear viscoelastic models are defined. These models are simulated using the ABAQUS finite element platform and compared with the obtained experimental data.

摘要

能够为用户提供逼真视觉和触觉反馈的交互式手术模拟器,是医学培训和手术规划领域一项很有前景的技术。然而,为手术模拟对人体器官和组织的物理行为进行建模仍然是一项挑战。一方面,这是因为难以表征生物软组织的物理特性。另一方面,交互式系统所需的实时模拟在计算时间要求方面的挑战依然存在。实时手术模拟和医学培训必须采用足够准确且简单的软组织模型,以便提供逼真的触觉和视觉响应。本研究试图在与手术过程相似的条件下对脑组织进行表征。出于这个目的,作为人类大脑的替代物,猪脑组织在低应变速率和大应变条件下,在旋转流变仪上进行了表征。为了以足够的准确性和简单性对脑组织进行建模,定义了线性弹性、超弹性和准线性粘弹性模型。使用ABAQUS有限元平台对这些模型进行了模拟,并与获得的实验数据进行了比较。

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