Grover Davinder S, Smith Oluwatosin, Fellman Ronald L, Godfrey David G, Butler Michelle R, Montes de Oca Ildamaris, Feuer William J
Glaucoma Associates of Texas, Dallas, Texas, USA.
Unidad Oftalmologica Montego c.a, Barquisimeto, Venezuela.
Br J Ophthalmol. 2015 Aug;99(8):1092-6. doi: 10.1136/bjophthalmol-2014-306269. Epub 2015 Feb 12.
BACKGROUND/AIMS: To introduce a novel ab interno 360° trabeculotomy for treating primary congenital glaucoma (PCG) and juvenile open angle glaucoma (JOAG) and report preliminary results.
A retrospective chart review of patients who underwent a gonioscopy assisted transluminal trabeculotomy (GATT) procedure by four of the authors (DSG, OS, RLF and DGG) between October 2011 and October 2013. The surgery was performed in patients ≤30 years old with a dysgenic anterior segment angle and uncontrolled PCG and JOAG.
Fourteen eyes of 10 patients underwent GATT with follow-up >12 months (12-33 months; mean 20.4). Patients ranged in age from 17 months to 30 years (mean=18.4 years), and five (50%) were female patients. No complications occurred during or following surgery except for early postoperative hyphema in five (36%) of eyes, all cleared by 1 month. The mean intraocular pressure (IOP) decreased from 27.3 to 14.8 mm Hg and the mean number of medications required decreased from 2.6 to 0.86. Five eyes had a drop in IOP ≥15 mm Hg (range 15-39).
The preliminary results and safety for GATT, a minimally invasive conjunctival sparing circumferential trabeculotomy, are promising and at least equivalent to previous results for ab externo trabeculotomy for the treatment of PCG and JOAG. All eyes in the study were considered a clinical success.
背景/目的:介绍一种新型的经内路360°小梁切开术治疗原发性先天性青光眼(PCG)和青少年开角型青光眼(JOAG)并报告初步结果。
对2011年10月至2013年10月间由四位作者(DSG、OS、RLF和DGG)进行房角镜辅助经腔小梁切开术(GATT)的患者进行回顾性病历分析。手术针对年龄≤30岁、前段房角发育异常且PCG和JOAG控制不佳的患者。
10例患者的14只眼接受了GATT,随访时间>12个月(12 - 33个月;平均20.4个月)。患者年龄从17个月至30岁不等(平均 = 18.4岁),5例(50%)为女性患者。手术期间及术后除5只眼(36%)出现早期术后前房积血外无其他并发症,所有积血均在1个月内吸收。平均眼压(IOP)从27.3 mmHg降至14.8 mmHg,所需药物平均数量从2.6种降至0.86种。5只眼的眼压下降≥15 mmHg(范围15 - 39)。
GATT作为一种微创的保留结膜的环形小梁切开术,其初步结果和安全性令人鼓舞,至少与以往外路小梁切开术治疗PCG和JOAG的结果相当。该研究中的所有眼均被视为临床成功。