Chan R C, Tam J S, Fok T F, French G L
Department of Microbiology, Chinese University of Hong Kong.
J Hosp Infect. 1989 May;13(4):367-75. doi: 10.1016/0195-6701(89)90056-x.
During January and February 1988 an outbreak of nosocomial rotavirus infection occurred in a special-care baby unit (SCBU). Seven infants were affected, of whom five had symptoms of diarrhoea. Typing by RNA electrophoresis (electropherotyping) demonstrated that a single rotavirus strain was responsible for the outbreak. The epidemic electropherotype was introduced by an infant with diarrhoea admitted directly into the SCBU from the community. Eight other electropherotypes were identified during January and February in patients with community-acquired rotavirus diarrhoea on other paediatric wards, but the outbreak strain occurred only on the SCBU. Electropherotyping is a useful and rapid method for tracing the epidemiology of hospital-acquired rotavirus infection.
1988年1月和2月期间，一家特殊护理婴儿病房（SCBU）发生了医院内轮状病毒感染暴发。7名婴儿受到影响，其中5名出现腹泻症状。通过RNA电泳（电泳分型）进行分型显示，单一轮状病毒株导致了此次暴发。该流行电泳型是由一名直接从社区转入SCBU的腹泻婴儿引入的。1月和2月期间，在其他儿科病房患有社区获得性轮状病毒腹泻的患者中还鉴定出了其他8种电泳型，但暴发株仅出现在SCBU。电泳分型是追踪医院获得性轮状病毒感染流行病学的一种有用且快速的方法。
