减压病中的脑灌注不足。

Cerebral perfusion deficits in dysbaric illness.

作者信息

Adkisson G H, Macleod M A, Hodgson M, Sykes J J, Smith F, Strack C, Torok Z, Pearson R R

机构信息

Institute of Naval Medicine, Alverstoke, Hants.

出版信息

Lancet. 1989 Jul 15;2(8655):119-22. doi: 10.1016/s0140-6736(89)90180-3.

DOI:10.1016/s0140-6736(89)90180-3

PMID:2567892

Abstract

Decompression sickness (DCS) is usually categorised as type I (mild; peripheral pain, non-neurological) or type II (serious; neurological). Type II is regarded as predominantly a spinal cord disease with infrequent cerebral involvement. Cerebral perfusion was studied by injection of 99Tcm-hexamethylpropyleneamine oxime and single photon emission tomography in 28 divers with confirmed incidents of DCS and cerebral arterial gas embolism (CAGE). Cerebral perfusion deficits were present in all 23 cases of type II DCS and in all 4 cases of CAGE. No deficits were present in the single case of type I DCS. Type II DCS should be recognised as a diffuse, multifocal, central nervous system disease.

摘要

减压病（DCS）通常分为I型（轻度；周围疼痛，非神经型）或II型（重度；神经型）。II型主要被视为一种脊髓疾病，脑部受累较少见。通过注射99Tcm-六甲基丙烯胺肟并采用单光子发射断层扫描技术，对28例确诊为减压病和脑动脉气体栓塞（CAGE）的潜水员进行了脑灌注研究。在所有23例II型减压病病例和所有4例脑动脉气体栓塞病例中均存在脑灌注缺损。I型减压病的单一病例中未出现缺损。II型减压病应被视为一种弥漫性、多灶性中枢神经系统疾病。