• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Vogt-小柳-原田综合征免疫抑制治疗的长期病程]

[Long-term course of immunosuppressive therapy of Vogt-Koyanagi-Harada syndrome].

作者信息

Wand K, Abraham S, Loos D, Stumpfe S, Lohmann C, Maier M, Feucht N

机构信息

Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675, München, Deutschland.

出版信息

Ophthalmologe. 2015 Oct;112(10):857-60. doi: 10.1007/s00347-015-3238-x.

DOI:10.1007/s00347-015-3238-x
PMID:25680347
Abstract

This article describes the case of a 22-year old female patient, who first presented with holocephalic headaches and bilateral loss in vision. After diagnosis of a complete Vogt-Koyanagi-Harada syndrome, high-dose corticosteroid therapy was initiated. Due to recurrent headaches 6 weeks later, immunosuppressive therapy was initiated with cyclosporine A. Because of an adverse effect (hirsutism) treatment was changed to azathioprine. In a long-term follow-up over 2 years the patient showed stable clinical findings with good visual acuity.

摘要

本文描述了一名22岁女性患者的病例,该患者最初表现为全头部头痛和双侧视力丧失。在诊断为完全性Vogt-小柳-原田综合征后,开始使用大剂量皮质类固醇治疗。6周后由于复发性头痛,开始使用环孢素A进行免疫抑制治疗。由于出现不良反应(多毛症),治疗改为硫唑嘌呤。在超过2年的长期随访中,患者的临床症状稳定,视力良好。

相似文献

1
[Long-term course of immunosuppressive therapy of Vogt-Koyanagi-Harada syndrome].[Vogt-小柳-原田综合征免疫抑制治疗的长期病程]
Ophthalmologe. 2015 Oct;112(10):857-60. doi: 10.1007/s00347-015-3238-x.
2
Triple agent immunosuppressive therapy in Vogt-Koyanagi-Harada syndrome.伏格特-小柳-原田综合征的三联免疫抑制治疗
Ocul Immunol Inflamm. 2006 Dec;14(6):333-9. doi: 10.1080/09273940600976938.
3
The use of low-dose azathioprine in patients with Vogt-Koyanagi-Harada disease.低剂量硫唑嘌呤在Vogt-小柳-原田病患者中的应用。
Ocul Immunol Inflamm. 2007 Sep-Oct;15(5):381-7. doi: 10.1080/09273940701624312.
4
Prevalence, clinical characteristics, and causes of vision loss in children with Vogt-Koyanagi-Harada disease in South India.印度南部 Vogt-Koyanagi-Harada 病患儿的患病率、临床特征和致盲原因。
Retina. 2010 Jul-Aug;30(7):1113-21. doi: 10.1097/IAE.0b013e3181c96a87.
5
[Recurrent uveitis with bilateral exudative retinal detachment. 10-year-old boy with bilaterally impaired vision and eye pain. Vogt-Koyanagi-Harada syndrome].[复发性葡萄膜炎伴双侧渗出性视网膜脱离。10岁男孩,双侧视力受损且眼痛。伏格特-小柳-原田综合征]
Ophthalmologe. 2004 Apr;101(4):390-3. doi: 10.1007/s00347-003-0792-4. Epub 2003 Jun 7.
6
Prognostic factors for clinical outcomes in patients with Vogt-Koyanagi-Harada disease treated with high-dose corticosteroids.大剂量皮质类固醇治疗 Vogt-Koyanagi-Harada 病患者的临床转归的预后因素。
Acta Ophthalmol. 2013 Sep;91(6):e486-93. doi: 10.1111/aos.12127. Epub 2013 Apr 10.
7
[Vogt Koyanagi Harada syndrome in children: diagnosis and management].
Bull Soc Belge Ophtalmol. 2010(314):15-8.
8
Vogt-Koyanagi-Harada syndrome: importance of early treatment.
Acta Neurol Belg. 2020 Oct;120(5):1217-1219. doi: 10.1007/s13760-020-01273-x. Epub 2020 Jan 11.
9
Vogt-Koyanagi-Harada syndrome in children: report of a case and review of the literature.儿童Vogt-小柳-原田综合征:一例报告并文献复习
Ocul Immunol Inflamm. 2007 Jul-Aug;15(4):351-7. doi: 10.1080/09273940701459453.
10
[Vogt-Koyanagi-Harada syndrome in children].[儿童Vogt-小柳-原田综合征]
J Fr Ophtalmol. 2002 Jun;25(6):636-40.

本文引用的文献

1
Resolution of subretinal fluid with systemic corticosteroid treatment in acute Vogt-Koyanagi-Harada disease.在急性 Vogt-Koyanagi-Harada 病中,全身皮质类固醇治疗可使视网膜下液消退。
Br J Ophthalmol. 2012 Nov;96(11):1410-4. doi: 10.1136/bjophthalmol-2012-301857. Epub 2012 Aug 31.
2
Vogt-Koyanagi-Harada disease: diagnosis and treatments update.Vogt-Koyanagi-Harada 病:诊断和治疗进展。
Curr Opin Ophthalmol. 2010 Nov;21(6):430-5. doi: 10.1097/ICU.0b013e32833eb78c.
3
Comparison of the clinical efficacy of two different immunosuppressive regimens in patients with chronic vogt-koyanagi-harada disease.
比较两种不同免疫抑制方案治疗慢性 vogt-koyanagi-harada 病的临床疗效。
Ocul Immunol Inflamm. 2010 Jun;18(3):200-7. doi: 10.3109/09273941003587541.
4
[Choroiditis].[脉络膜炎]
Ophthalmologe. 2010 Jan;107(1):79-93. doi: 10.1007/s00347-009-2116-9.
5
Vogt-koyanagi-harada syndrome.伏格特-小柳-原田综合征
Curr Eye Res. 2008 Jul;33(7):517-23. doi: 10.1080/02713680802233968.
6
The use of low-dose azathioprine in patients with Vogt-Koyanagi-Harada disease.低剂量硫唑嘌呤在Vogt-小柳-原田病患者中的应用。
Ocul Immunol Inflamm. 2007 Sep-Oct;15(5):381-7. doi: 10.1080/09273940701624312.
7
Evaluation of the effect on outcomes of the route of administration of corticosteroids in acute Vogt-Koyanagi-Harada disease.评估急性Vogt-小柳-原田病中糖皮质激素给药途径对预后的影响。
Am J Ophthalmol. 2006 Jul;142(1):119-24. doi: 10.1016/j.ajo.2006.02.049.
8
Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature.Vogt-小柳-原田病修订诊断标准:国际命名委员会报告
Am J Ophthalmol. 2001 May;131(5):647-52. doi: 10.1016/s0002-9394(01)00925-4.
9
Vogt-Koyanagi-Harada syndrome.伏格特-小柳-原田综合征
Surv Ophthalmol. 1995 Jan-Feb;39(4):265-92. doi: 10.1016/s0039-6257(05)80105-5.