金黄色葡萄球菌在鼻息肉肥大细胞内的细胞内驻留：一项新观察。 - Suppr

Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation.

作者信息

Hayes Stephen M, Howlin Robert, Johnston David A, Webb Jeremy S, Clarke Stuart C, Stoodley Paul, Harries Philip G, Wilson Susan J, Pender Sylvia L F, Faust Saul N, Hall-Stoodley Luanne, Salib Rami J

机构信息

Southampton NIHR Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, Southampton, United Kingdom; University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; University of Southampton, Southampton, United Kingdom.

Southampton NIHR Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, Southampton, United Kingdom; University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, Southampton, United Kingdom.

出版信息

J Allergy Clin Immunol. 2015 Jun;135(6):1648-51. doi: 10.1016/j.jaci.2014.12.1929. Epub 2015 Feb 11.

DOI:10.1016/j.jaci.2014.12.1929

PMID:25680455

Abstract

摘要

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Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation.金黄色葡萄球菌在鼻息肉肥大细胞内的细胞内驻留：一项新观察。

J Allergy Clin Immunol. 2015 Jun;135(6):1648-51. doi: 10.1016/j.jaci.2014.12.1929. Epub 2015 Feb 11.

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Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps.金黄色葡萄球菌可增强健康鼻腔组织中的紧密连接屏障完整性，但对鼻息肉则无此作用。

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Staphylococcus aureus invades the epithelium in nasal polyposis and induces IL-6 in nasal epithelial cells in vitro.金黄色葡萄球菌侵袭鼻息肉中的上皮细胞，并在体外诱导鼻上皮细胞产生白细胞介素-6。

Allergy. 2010 Nov;65(11):1430-7. doi: 10.1111/j.1398-9995.2010.02381.x.

Chronic rhinosinusitis (CRS) and CRS with nasal polyposis (CRSwNP).慢性鼻-鼻窦炎（CRS）和伴鼻息肉的慢性鼻-鼻窦炎（CRSwNP）。

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Chronic rhinosinusitis with nasal polyps: elevated serum immunoglobulin E is associated with Staphylococcus aureus on culture.慢性鼻-鼻窦炎伴鼻息肉：培养时血清免疫球蛋白 E 升高与金黄色葡萄球菌有关。

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IFAR AUGUST EDITORIAL.国际抗病毒研究协会八月社论。

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Bacterial biofilms and the pathophysiology of chronic rhinosinusitis.细菌生物膜与慢性鼻-鼻窦炎的病理生理学

Curr Opin Allergy Clin Immunol. 2011 Feb;11(1):18-23. doi: 10.1097/ACI.0b013e3283423376.

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Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease.致病性共生菌触发的上皮细胞吲哚胺2,3-双加氧酶1的诱导驱动炎症性肠病的区域易感性。

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Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells.金黄色葡萄球菌利用细胞内半胱氨酸蛋白酶 staphostatin A 诱导上皮细胞发生宿主细胞死亡。

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Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation.

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