Lu Lei, Sun RongRong, Liu Min, Zheng Yi, Zhang Peiying
Graduate School, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, China.
Department of Cardiology, Xuzhou Central Hospital, Affiliated Xuzhou Hospital, Medical School of Southeast University, Xuzhou Clinical Medical College of Nanjing University of Chinese Medicine, 199# South Jiefang Road, Xuzhou, 221009, Jiangsu, China.
Cell Biochem Biophys. 2015 Jul;72(3):851-5. doi: 10.1007/s12013-015-0550-7.
The inflammation of the heart muscles, such as myocarditis, the membrane sac which surrounds the heart called as pericarditis, and the inner lining of the heart or the myocardium, heart muscle as endocarditis are known as the inflammatory heart diseases. Inflammation of heart is caused by known infectious agents, viruses, bacteria, fungi or parasites, and by toxic materials from the environment, water, food, air, toxic gases, smoke, and pollution, or by an unknown origin. Myocarditis is induced by infection of heart muscle by virus like sarcoidosis and immune diseases. The symptoms include chest pain, angina, pain in heart muscle, and shortness of breath, edema, swelling of feet or ankles, and fatigue. The ECG, X-ray, and MRI can diagnose the disease; blood test and rise in enzymes levels provide abnormality in heart function. The treatment includes use of antibiotics for inflammation of heart muscle and medications. The ultrasound imaging indicates further damage to the heart muscle. In severe cases of infection heart failure can occur so long-term medications are necessary to control inflammation. The various biomarkers are reported for the inflammatory heart diseases. The causes, symptoms and treatments of inflammatory heart diseases are described.
心肌的炎症,如心肌炎;包围心脏的膜囊炎症,即心包炎;以及心脏内层或心肌内膜的炎症,即心内膜炎,都被称为炎症性心脏病。心脏炎症由已知的感染因子引起,如病毒、细菌、真菌或寄生虫,也可由环境中的有毒物质引起,如水、食物、空气、有毒气体、烟雾和污染,或由不明原因引起。心肌炎由病毒感染心肌诱发,如结节病和免疫性疾病。症状包括胸痛、心绞痛、心肌疼痛、呼吸急促、水肿、脚踝或脚部肿胀以及疲劳。心电图、X射线和磁共振成像可诊断该病;血液检测和酶水平升高表明心脏功能异常。治疗包括使用抗生素治疗心肌炎症以及药物治疗。超声成像显示心肌有进一步损伤。在严重感染的情况下可能会发生心力衰竭,因此需要长期用药来控制炎症。针对炎症性心脏病报道了各种生物标志物。本文描述了炎症性心脏病的病因、症状和治疗方法。