Rey M J, Schulz P, Costa C, Dick P, Tissot R
Department of Psychiatry, Domaine Bel-Air, Chêne-Bourg, Geneva, Switzerland.
Int Clin Psychopharmacol. 1989 Apr;4(2):95-104. doi: 10.1097/00004850-198904000-00001.
Chlorpromazine (CPZ) equivalents are often used as a relative measure of the antipsychotic potency of neuroleptics. We review the CPZ equivalents of 33 neuroleptics and illustrate why imprecisions or discrepancies will be difficult to eliminate from these values. We nevertheless underline that CPZ equivalents can be clinically useful, since they facilitate the choice of doses of different neuroleptics that should induce comparable antipsychotic effects.
氯丙嗪（CPZ）等效剂量常被用作衡量抗精神病药物效力的相对指标。我们回顾了33种抗精神病药物的CPZ等效剂量，并阐述了为何难以消除这些数值中的不精确性或差异。然而，我们强调CPZ等效剂量在临床上仍有实用价值，因为它们有助于选择不同抗精神病药物的剂量，这些剂量应能产生相当的抗精神病效果。
