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本文引用的文献

1
Discrepancies between surveillance definition and the clinical incidence of Clostridium difficile infection in a Veterans Affairs long-term care facility.退伍军人事务部长期护理机构中艰难梭菌感染监测定义与临床发病率之间的差异。
Infect Control Hosp Epidemiol. 2014 Nov;35(11):1435-6. doi: 10.1086/678434.
2
Clostridium difficile ribotype 027 is most prevalent among inpatients admitted from long-term care facilities.艰难梭菌核糖体分型027在从长期护理机构收治的住院患者中最为常见。
J Hosp Infect. 2014 Dec;88(4):218-21. doi: 10.1016/j.jhin.2014.06.016. Epub 2014 Jul 30.
3
infection in older adults.老年人感染
Aging health. 2013 Aug 1;9(4):403-414. doi: 10.2217/ahe.13.37.
4
Outpatient antibiotic prescribing in the United States: 2000 to 2010.美国门诊抗生素处方情况：2000年至2010年
BMC Med. 2014 Jun 11;12:96. doi: 10.1186/1741-7015-12-96.
5
Strategies to prevent Clostridium difficile infections in acute care hospitals: 2014 Update.急性护理医院预防艰难梭菌感染的策略：2014年更新版
Infect Control Hosp Epidemiol. 2014 Jun;35(6):628-45. doi: 10.1086/676023.
6
Cost-effectiveness of competing strategies for management of recurrent Clostridium difficile infection: a decision analysis.复发性艰难梭菌感染管理的竞争策略的成本效益：一项决策分析
Clin Infect Dis. 2014 Jun;58(11):1507-14. doi: 10.1093/cid/ciu128. Epub 2014 Mar 31.
7
Mathematical modelling reveals properties of TcdC required for it to be a negative regulator of toxin production in Clostridium difficile.数学建模揭示了艰难梭菌中TcdC作为毒素产生负调节因子所需的特性。
J Math Biol. 2015 Mar;70(4):773-804. doi: 10.1007/s00285-014-0780-0. Epub 2014 Apr 1.
8
Multistate point-prevalence survey of health care-associated infections.多州医疗机构相关性感染的时点患病率调查。
N Engl J Med. 2014 Mar 27;370(13):1198-208. doi: 10.1056/NEJMoa1306801.
9
Risk estimation for recurrent Clostridium difficile infection based on clinical factors.基于临床因素的复发性艰难梭菌感染风险评估。
Clin Infect Dis. 2014 May;58(10):1386-93. doi: 10.1093/cid/ciu107. Epub 2014 Mar 5.
10
Antimicrobial stewardship in long term care facilities: what is effective?长期护理机构中的抗菌药物管理：什么是有效的？
Antimicrob Resist Infect Control. 2014 Feb 12;3(1):6. doi: 10.1186/2047-2994-3-6.

在长期护理机构中：预防与管理。

in the Long-Term Care Facility: Prevention and Management.

作者信息

Jump Robin L P, Donskey Curtis J

机构信息

Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio ; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western, Reserve University, Cleveland, Ohio.

Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio ; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western, Reserve University, Cleveland, Ohio ; Research Service, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio.

出版信息

Curr Geriatr Rep. 2015 Mar;4(1):60-69. doi: 10.1007/s13670-014-0108-3.

DOI:10.1007/s13670-014-0108-3
PMID:25685657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4322371/
Abstract

Residents of long-term care facilities are at high risk for infection due to frequent antibiotic exposure in a population already rendered vulnerable to infection due to advanced age, multiple comorbid conditions and communal living conditions. Moreover, asymptomatic carriage of toxigenic and recurrent infections are prevalent in this population. Here, we discuss epidemiology and management of infection among residents of long-term care facilities. Also, recognizing that both the population and culture differs significantly from that of hospitals, we also address prevention strategies specific to LTCFs.

摘要

长期护理机构的居民由于年事已高、多种合并症以及集体生活条件，本身就容易感染，又因频繁接触抗生素，感染风险很高。此外，该人群中产生毒素的无症状携带和反复感染很普遍。在此，我们讨论长期护理机构居民感染的流行病学和管理。同时，认识到该人群和文化与医院有很大不同，我们还探讨了长期护理机构特有的预防策略。