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印度年轻成年人中高血压与高血糖之间的相关性。

Correlation between hypertension and hyperglycemia among young adults in India.

作者信息

Midha Tanu, Krishna Vinay, Shukla Rishi, Katiyar Praveen, Kaur Samarjeet, Martolia Dinesh Singh, Pandey Umeshwar, Rao Yashwant Kumar

机构信息

Tanu Midha, Dinesh Singh Martolia, Department of Community Medicine, Government Medical College, Kannauj, Uttar Pradesh 209732, India.

出版信息

World J Clin Cases. 2015 Feb 16;3(2):171-9. doi: 10.12998/wjcc.v3.i2.171.

Abstract

AIM

To assess the correlation between blood pressure levels and fasting plasma glucose levels among young adults attending Chatrapati Shahuji Maharaj University, Kanpur, India.

METHODS

The present study was cross-sectional in nature, conducted among students in the Institute of Paramedical Sciences, Chatrapati Shahuji Maharaj University, Kanpur. Study subjects included 185 young adults. Among them, 94 were males and 91 were females, in the age group 17 to 19 years.

RESULTS

Mean age among males was 18.5 ± 1.5 years and among females was 17.9 ± 1.8 years. Of the total 185 study subjects, 61 (32.9%) were classified as pre-diabetic and 20 (10.8%) as pre-hypertensive. Mean waist circumference, systolic blood pressure and serum high density lipoprotein did not vary significantly between normoglycemic and pre-diabetic subjects. However, the mean diastolic blood pressure of pre-diabetics (82 ± 5 mmHg) was significantly higher than normoglycemics (79 ± 6 mmHg). Mean serum cholesterol, serum triglycerides, serum low density lipoprotein (LDL) and serum very low density lipoprotein was also higher among pre-diabetic subjects in comparison to normoglycemic subjects and the difference was statistically significant. Upon multiple linear regression analysis, it was observed that body mass index (BMI) (β = 0.149), diastolic blood pressure (β = 0.375) and serum LDL (β = 0.483) were significantly associated with fasting plasma glucose. Multiple linear regression with diastolic blood pressure as the outcome variable showed that BMI (β = 0.219), fasting blood glucose (β = 0.247) and systolic blood pressure (β = 0.510) were significantly associated.

CONCLUSION

A significant prevalence of pre-diabetes and pre-hypertension in young adults is a matter of concern therefore all young adults need to be targeted for screening of diabetes and hypertension and lifestyle modification.

摘要

目的

评估印度坎普尔市查特拉帕蒂·沙胡吉·马哈拉杰大学的年轻成年人中血压水平与空腹血糖水平之间的相关性。

方法

本研究为横断面研究,在坎普尔市查特拉帕蒂·沙胡吉·马哈拉杰大学的辅助医疗科学研究所的学生中进行。研究对象包括185名年轻成年人。其中,94名男性,91名女性,年龄在17至19岁之间。

结果

男性的平均年龄为18.5±1.5岁,女性为17.9±1.8岁。在总共185名研究对象中,61名(32.9%)被归类为糖尿病前期,20名(10.8%)为高血压前期。血糖正常和糖尿病前期受试者之间的平均腰围、收缩压和血清高密度脂蛋白没有显著差异。然而,糖尿病前期患者的平均舒张压(82±5mmHg)显著高于血糖正常者(79±6mmHg)。与血糖正常的受试者相比,糖尿病前期受试者的平均血清胆固醇、血清甘油三酯、血清低密度脂蛋白(LDL)和血清极低密度脂蛋白也更高,且差异具有统计学意义。经多元线性回归分析发现,体重指数(BMI)(β=0.149)、舒张压(β=0.375)和血清LDL(β=0.483)与空腹血糖显著相关。以舒张压为结果变量的多元线性回归显示,BMI(β=0.219)、空腹血糖(β=0.247)和收缩压(β=0.510)显著相关。

结论

年轻成年人中糖尿病前期和高血压前期的患病率较高,令人担忧,因此所有年轻成年人都需要作为糖尿病和高血压筛查以及生活方式改变的目标人群。

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