可见光诱导的邻碘苯基丙烯酰胺自由基环化反应：吲哚啉-2-酮的简洁合成
Visible light induced radical cyclization of o-iodophenylacrylamides: a concise synthesis of indolin-2-one.
作者信息
Dong Wuheng, Liu Yan, Hu Bei, Ren Kai, Li Yuyuan, Xie Xiaomin, Jiang Yuexiu, Zhang Zhaoguo
机构信息
School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
出版信息
Chem Commun (Camb). 2015 Mar 18;51(22):4587-90. doi: 10.1039/c5cc00072f.
PMID:25688002
Abstract
A [Ir(ppy)2(dtb-bpy)]PF6-catalyzed intramolecular radical cyclization of o-iodophenylacrylamides affording indolin-2-ones in moderate to excellent yields via 5-exo-trig radical cyclization under visible light is presented. This method provides new access to the synthesis of indolin-2-ones under mild reaction conditions.
摘要
报道了一种[Ir(ppy)₂(dtb - bpy)]PF₆催化的邻碘苯基丙烯酰胺分子内自由基环化反应，该反应在可见光下通过5 - exo - trig自由基环化以中等至优异的产率得到吲哚啉 - 2 - 酮。该方法为在温和反应条件下合成吲哚啉 - 2 - 酮提供了新的途径。
Zotero 插件