Centre for Ophthalmology, University Hospital Tübingen, Schleichstr. 12-16, 72076, Tübingen, Germany,
Graefes Arch Clin Exp Ophthalmol. 2015 May;253(5):779-84. doi: 10.1007/s00417-015-2955-9. Epub 2015 Feb 18.
To investigate the safety and efficacy of intraoperative conversion of unsuccessful canaloplasty technique into 180-degree metal or 360-degree suture trabeculotomy.
In this retrospective observational case series, 35 eyes of 35 patients with open-angle glaucoma (OAG) who had undergone unsuccessful canaloplasty technique and underwent intraoperative conversion were studied. In 17 eyes (group A), the procedure was converted into 180-degree metal trabeculotomy because of unsuccessful circumferential Schlemm's canal (SC) catheterisation. Group B included 18 eyes that were converted into 360-degree trabeculotomy because of cheese wiring of tension suture through the trabecular meshwork (TM) after successful complete catheterisation of SC.
Median preoperative IOP was 22.0 mmHg (range 16-34) in group A, and 22.0 mmHg (range 15-48) in group B. Median IOP was significantly reduced in both groups postoperatively, at the 12-month examination to 15.0 mmHg (range 9-21) representing a reduction of 36 % in group A, and to 14.5 mmHg (range 8-21) representing a reduction of 34 % in group B. Median glaucoma medication number decreased significantly from 4 (range 2-4) and 3 (range 1-4) preoperatively to 2 (range 0-4) and 1 (range 0-3) at 12 months in groups A and B respectively. Hyphema was the commonest complication, with an incidence of 76 % in group A and 78 % in group B.
180-degree metal or 360-degree suture/catheter trabeculotomy are safe and effective surgical backup methods to control IOP in cases of unsuccessful intracanalicular placement of tension suture during canaloplasty surgery.
探讨术中将失败的 canaloplasty 技术转换为 180 度金属小梁切开术或 360 度缝线小梁切开术的安全性和有效性。
在这项回顾性观察性病例系列研究中,对 35 例接受失败的 canaloplasty 技术且行术中转换的开角型青光眼(OAG)患者的 35 只眼进行了研究。在 17 只眼(A 组)中,由于 Schlemm 管(SC)导管环形置管不成功,将手术转换为 180 度金属小梁切开术。B 组包括 18 只眼,由于 SC 完全置管成功后张力缝线通过小梁网(TM)呈奶酪状布线,将手术转换为 360 度小梁切开术。
A 组术前平均眼压为 22.0mmHg(范围 16-34),B 组为 22.0mmHg(范围 15-48)。两组术后眼压均显著降低,12 个月检查时分别为 15.0mmHg(范围 9-21),降低了 36%,B 组为 14.5mmHg(范围 8-21),降低了 34%。A 组和 B 组术前平均降眼压药物数量分别从 4 种(范围 2-4)和 3 种(范围 1-4)降至 12 个月时的 2 种(范围 0-4)和 1 种(范围 0-3)。前房积血是最常见的并发症,A 组发生率为 76%,B 组为 78%。
在 canaloplasty 手术中,当张力缝线不能成功植入管内时,180 度金属小梁切开术或 360 度缝线/导管小梁切开术是控制眼压的安全有效手术后备方法。