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[风湿性疾病中肝转氨酶升高的鉴别诊断]

[Differential diagnosis of elevated liver transaminases in rheumatic diseases].

作者信息

Mayet W-J

机构信息

Zentrum für Innere Medizin, Nordwest-Krankenhaus Sanderbusch, Hauptstr., 26452, Sanderbusch, Deutschland,

出版信息

Z Rheumatol. 2015 Mar;74(2):137-45. doi: 10.1007/s00393-014-1501-1.

Abstract

During laboratory monitoring of patients with rheumatic diseases it is not uncommon to notice elevated liver transaminase levels. From a rheumatological perspective there are multiple causes for this. Liver dysfunction can be the result of certain rheumatological diseases, such as systemic lupus erythematosus. Primary biliary cirrhosis and primary sclerosing cholangitis are associated with rheumatic diseases. On the other hand, hepatological diseases, such as hepatitis C and autoimmune hepatitis show rheumatological symptoms. The most common cause of elevation of liver transaminase levels in rheumatic patients is without doubt the anti-rheumatic therapy.

摘要

在对风湿性疾病患者进行实验室监测时,经常会注意到肝转氨酶水平升高。从风湿病学角度来看,其原因是多方面的。肝功能障碍可能是某些风湿性疾病的结果,如系统性红斑狼疮。原发性胆汁性肝硬化和原发性硬化性胆管炎与风湿性疾病相关。另一方面,丙型肝炎和自身免疫性肝炎等肝脏疾病也会出现风湿性症状。毫无疑问,风湿性疾病患者肝转氨酶水平升高的最常见原因是抗风湿治疗。

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