Kim Whan B, Alavi Afsaneh, Pope Elena, Walsh Scott
McMaster University, Hamilton, Ontario, Canada
University of Toronto, Toronto, Ontario, Canada Women's College Hospital, Toronto, Ontario, Canada.
Int J Low Extrem Wounds. 2015 Jun;14(2):196-9. doi: 10.1177/1534734615572469. Epub 2015 Feb 17.
Epidermolysis bullosa (EB) pruriginosa is a rare clinical subtype of dystrophic epidermolysis bullosa (DEB) that is characterized by intense pruritus resulting in hypertrophic, lichenified, prurigo-like plaques and nodules secondary to scratching. The variability in the age of onset, rarity of intact bullae, histologic ambiguities, and close resemblance to other conditions such as acquired inflammatory dermatoses may make diagnosis difficult for this unusual condition, for which fewer than 100 cases have been documented. In this report, we describe 3 cases of EB pruriginosa and review the current literature.
大疱性表皮松解症（EB）瘙痒型是营养不良性大疱性表皮松解症（DEB）的一种罕见临床亚型，其特征为剧烈瘙痒，搔抓后导致肥厚性、苔藓化、痒疹样斑块和结节。发病年龄的变异性、完整水疱的罕见性、组织学上的不明确性以及与其他疾病（如获得性炎症性皮肤病）的高度相似性，可能使这种罕见疾病的诊断变得困难，目前记录在案的病例不足100例。在本报告中，我们描述了3例EB瘙痒型病例并回顾了当前文献。
