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成功用糖皮质激素治疗由结节病引起的继发性范可尼综合征。

Successful treatment with glucocorticoid for secondary Fanconi syndrome caused by sarcoidosis.

机构信息

a Department of General Medicine , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama , Japan.

b Department of Medicine and Clinical Science , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences , Okayama , Japan.

出版信息

Mod Rheumatol. 2017 May;27(3):545-547. doi: 10.3109/14397595.2014.1002163. Epub 2015 Jul 29.

DOI:10.3109/14397595.2014.1002163
PMID:25698227
Abstract

A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.

摘要

一位 77 岁女性,存在肾功能障碍、高钙血症和高钙尿症。全身检查包括肾活检显示患者患有继发于肾结节病的范可尼综合征。开始每天用 25 毫克泼尼松龙进行治疗,病情得到改善。结节病患者范可尼综合征的并发症极为罕见。虽然病理机制尚不清楚,但皮质类固醇治疗对改善蛋白尿、糖尿、高钙尿和氨基酸尿有效。

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