孤立性鼻旁窦结节病伴颅内扩展：病例报告
Isolated sinonasal sarcoidosis with intracranial extension: case report.
作者信息
Dessouky O Y
机构信息
Department of Otolaryngology-Head and Neck Surgery, Ain Shams University, Cairo, Egypt.
出版信息
Acta Otorhinolaryngol Ital. 2008 Dec;28(6):306-8.
The case is presented of a 20-year-old female who was incidentally diagnosed with isolated sarcoidosis in the form of a nasal mass involving the ethmoid sinuses with destruction of the cribriform plate and intracranial extension. The patient complained of cacosmia and nasal obstruction. Histopathologic examination of biopsies from the nasal mass led to a diagnosis of non-caseating granuloma, highly suggestive of sarcoidosis. No systemic manifestations were detected, and the patient was started on a regimen of systemic steroids. Over the 3 months following biopsy and commencement of systemic steroids, the patient showed improvement in symptoms, and computed tomography of the paranasal sinuses revealed complete resolution of the sinonasal mass. Follow-up for one year revealed no recurrence.
本文报告了一例20岁女性患者，该患者偶然被诊断为孤立性结节病，表现为鼻腔肿物累及筛窦，伴有筛板破坏及颅内扩展。患者主诉嗅觉障碍和鼻塞。对鼻腔肿物活检组织进行组织病理学检查，诊断为非干酪样肉芽肿，高度提示结节病。未发现全身表现，遂开始给予患者全身用类固醇治疗方案。在活检及开始全身用类固醇治疗后的3个月里，患者症状有所改善，鼻窦计算机断层扫描显示鼻窦肿物完全消退。随访一年未发现复发。
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