Noronen Katariina, Laukontaus Sani, Kantonen Ilkka, Aho Pekka, Albäck Anders, Venermo Maarit
Helsinki University, Helsinki University Central Hospital, Finland.
Vasa. 2015 Mar;44(2):115-21. doi: 10.1024/0301-1526/a000416.
The risk of rupture for a large (≥ 55 mm) abdominal aortic aneurysm(AAA) is significant and therefore operative treatment should take place before possible aneurysm rupture. Timing of elective AAA surgery has rarely been investigated previously. The aim of this study is to evaluate success in the elective treatment process of large AAAs from referral to surgery in Helsinki University Central Hospital.
We retrospectively analyzed all 361 patients who were assigned for elective treatment of AAA during 2005 - 2010. We divided the patients into subgroups according to size of the aneurysm: <60 mm, 61 - 70 mm and >70 mm. The main focus was set on the preoperative period and on potential factors causing delay. End points indicating failure in the treatment process were aneurysm ruptures and deaths before surgery.
The median time from referral to surgery for the three subgroups was 112, 91 and 45 days respectively (p < 0,001). There were no significant differences between the treatment methods: open repair (OR) with 103 days and endovascular aortic repair (EVAR) with 113 days until surgery. Twenty three (6.4 %) patients were operated on emergency basis while waiting for the operation, six of them for ruptured aneurysm. There were an additional five patients with aneurysm ruptures who all died, as did four out the six operated ones.
The whole treatment process starting from the referral should be considered in order for elective AAA treatment to succeed. Recommendations should be established for the preoperative period to guarantee rapid preoperative evaluation.
大型(≥55mm)腹主动脉瘤(AAA)破裂风险很大,因此手术治疗应在动脉瘤可能破裂之前进行。此前很少有人研究择期AAA手术的时机。本研究的目的是评估赫尔辛基大学中心医院从转诊到手术的大型AAA择期治疗过程的成功率。
我们回顾性分析了2005年至2010年期间被分配接受AAA择期治疗的所有361例患者。我们根据动脉瘤大小将患者分为亚组:<60mm、61 - 70mm和>70mm。主要关注术前阶段以及导致延迟的潜在因素。表明治疗过程失败的终点是动脉瘤破裂和手术前死亡。
三个亚组从转诊到手术的中位时间分别为112天、91天和45天(p<0.001)。治疗方法之间无显著差异:开放修复(OR)至手术时间为103天,血管内主动脉修复(EVAR)至手术时间为113天。23例(6.4%)患者在等待手术期间接受了急诊手术,其中6例为动脉瘤破裂。另有5例动脉瘤破裂患者全部死亡,急诊手术的6例患者中有4例死亡。
为使AAA择期治疗成功,应考虑从转诊开始的整个治疗过程。应制定术前建议以确保快速的术前评估。