Internal Medicine, Emory University, Atlanta, GA, USA
Internal Medicine, Emory University, Atlanta, GA, USA.
Gastroenterol Rep (Oxf). 2015 Aug;3(3):201-8. doi: 10.1093/gastro/gov004. Epub 2015 Feb 18.
Gastrin is an important hormone of the digestive system, which assists gastric acid secretion. It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to common medications such as proton pump inhibitors. In this review we provide an overview of the pathophysiology and medical causes of hypergastrinemia, diagnostic testing and clinical consequences of chronic hypergastrinemia.
胃泌素是消化系统的一种重要激素,有助于胃酸分泌。在 Zollinger-Ellison 综合征等疾病中,或由于质子泵抑制剂等常见药物,胃泌素可能会病理性升高。在这篇综述中,我们概述了高胃泌素血症的病理生理学和医学病因、诊断检测以及慢性高胃泌素血症的临床后果。