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[曾接受过组胺H2受体拮抗剂治疗的十二指肠溃疡切除术后患者胃残端排空异常]

[Anomalies in gastric stump emptying of patients who have undergone resections for duodenal ulcer previously treated with histamine H2 receptor antagonists].

作者信息

Quaranta L, Segre D, Abbo L, Balestrino E, Clerico D, Emmolo I, Cardona R, Massimino S

出版信息

Minerva Chir. 1989 May 31;44(10):1475-8.

PMID:2570381
Abstract

The problem of obstructed emptying of the gastric stump after Billroth II operations in patients previously treated with H2 receptors is discussed. Statistical comparison using the Student's "t" test revealed a significant difference (t = 2.173) between those given and not given H2-antagonists and confirmed the existence of greater postoperative hypotonia in the gastric stumps of the former group. This clinical syndrome demands careful monitoring of the hydroelectrolytic balance and possibly the use of a double naso-gastric and nasojejunal tube as a precaution to ensure the delivery of the jejunal contents to the stomach. The gastrokinetic drugs metoclopramide and domperidone are also beneficial.

摘要

讨论了曾接受H2受体治疗的患者在毕罗Ⅱ式手术后胃残端排空受阻的问题。使用学生“t”检验进行的统计比较显示,给予和未给予H2拮抗剂的患者之间存在显著差异(t = 2.173),并证实前一组患者的胃残端术后肌张力降低更为明显。这种临床综合征需要仔细监测水电解质平衡,可能还需要使用双鼻胃管和鼻空肠管作为预防措施,以确保空肠内容物进入胃内。胃肠动力药物甲氧氯普胺和多潘立酮也有帮助。

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