接受和未接受激素治疗的绝经后女性以及男性的语言能力。
Language performance in postmenopausal women with and without hormone therapy and men.
作者信息
Lee Grace J, Curiel Ashley R, Miller Karen J, Amano Stacy, Gorsuch Richard, Small Gary W
机构信息
Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, CA 90024, USA.
Pepperdine University, Los Angeles, CA 90045, USA.
出版信息
Aging health. 2012;8(6):625-632. doi: 10.2217/ahe.12.66.
AIMS
In the current study, we explored the potential effects of hormone therapy (HT) on language functioning in healthy, postmenopausal women and compared them with men of similar ages.
MATERIALS & METHODS: Language functioning on tasks of verbal fluency and object naming was examined in 100 participants (mean age: 61.9 years; 33 HT users, 15 HT non-users and 52 men) at baseline and follow-up (mean follow-up time period: 2.6 years).
RESULTS
At baseline, men had higher composite language scores than HT users. However, HT users demonstrated more improvement over time compared with men, whereas HT non-users performed similarly to men, with no improvement over time. Longer duration of HT use was not associated with improved performance on language tests.
CONCLUSION
These results suggest an association between HT use and better language ability in postmenopausal women.
目的
在本研究中，我们探讨了激素疗法（HT）对健康绝经后女性语言功能的潜在影响，并将其与年龄相仿的男性进行比较。
材料与方法
在基线和随访时（平均随访时间段：2.6年），对100名参与者（平均年龄：61.9岁；33名激素疗法使用者、15名非激素疗法使用者和52名男性）进行了语言流畅性和物体命名任务的语言功能测试。
结果
在基线时，男性的综合语言得分高于激素疗法使用者。然而，与男性相比，激素疗法使用者随着时间推移表现出更大的改善，而非激素疗法使用者的表现与男性相似，且未随时间改善。激素疗法使用时间较长与语言测试成绩改善无关。
结论
这些结果表明，绝经后女性使用激素疗法与更好的语言能力之间存在关联。
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