一种基于人类连接组和7T磁共振成像的用于深部脑刺激的虚拟患者模拟器。
A Virtual Patient Simulator Based on Human Connectome and 7 T MRI for Deep Brain Stimulation.
作者信息
Bonmassar Giorgio, Angelone Leonardo M, Makris Nikos
机构信息
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA.
Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD.
出版信息
Int J Adv Life Sci. 2014;6(3-4):364-372.
Abstract
This paper presents a virtual model of patients with Deep Brain Stimulation implants. The model is based on Human Connectome and 7 Tesla Magnetic Resonance Imaging (MRI) data. We envision that the proposed virtual patient simulator will enable radio frequency power dosimetry on patients with deep brain stimulation implants undergoing MRI. Results from the proposed virtual patient study may facilitate the use of clinical MRI instead of computed tomography scans. The virtual patient will be flexible and morphable to relate to patient-specific neurological and psychiatric conditions such as Obsessive Compulsive Disorder, which benefit from deep brain stimulation.
摘要
本文展示了植入脑深部电刺激器患者的虚拟模型。该模型基于人类连接组和7特斯拉磁共振成像（MRI）数据。我们设想，所提出的虚拟患者模拟器将能够对接受MRI检查的植入脑深部电刺激器的患者进行射频功率剂量测定。所提出的虚拟患者研究结果可能有助于临床MRI的使用，而非计算机断层扫描。该虚拟患者将具有灵活性和可变形性，以关联特定患者的神经和精神疾病，如强迫症，这些疾病可受益于脑深部电刺激。
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