Javadi Mohammad-Ali, Feizi Sepehr
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Ophthalmic Vis Res. 2014 Oct-Dec;9(4):510-3. doi: 10.4103/2008-322X.150832.
To report a keratoconic eye that developed severe sterile keratitis and corneal scar after collagen crosslinking necessitating corneal transplantation.
A 26-year-old man with progressive keratoconus underwent collagen crosslinking and presented with severe keratitis 72 hours after the procedure. The initial impression was infectious corneal ulcer and a fortified antibiotic regimen was administered. However, the clinical course and confocal microscopy results prompted a diagnosis of sterile keratitis. The eye developed severe corneal scars leading to reduced visual acuity and necessitating corneal transplantation.
Sterile keratitis may develop after collagen crosslinking resulting in profound visual loss leading to corneal transplantation.
报告一例圆锥角膜患者在胶原交联术后发生严重无菌性角膜炎及角膜瘢痕，最终需要进行角膜移植。
一名26岁进行性圆锥角膜男性患者接受了胶原交联术，术后72小时出现严重角膜炎。最初考虑为感染性角膜溃疡，并给予强化抗生素治疗方案。然而，临床病程及共焦显微镜检查结果提示为无菌性角膜炎。该眼出现严重角膜瘢痕，导致视力下降，最终需要进行角膜移植。
胶原交联术后可能发生无菌性角膜炎，导致严重视力丧失，进而需要角膜移植。
