Li Bo, Liu Bin, Shi Bing-Feng
Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
Chem Commun (Camb). 2015 Mar 25;51(24):5093-6. doi: 10.1039/c5cc00531k.
Copper-catalyzed ortho-halogenation of C(sp(2))-H bonds directed by a PIP directing group with NXS (X = Cl, Br, I) has been developed. The reaction is scalable and tolerates a broad range of functional groups and heteroarenes, providing an efficient access to halogenated arenes and heteroarenes.
已开发出由PIP导向基团引导的、使用NXS（X = Cl、Br、I）对C(sp(2))-H键进行铜催化的邻位卤化反应。该反应具有可扩展性，能耐受多种官能团和杂芳烃，为卤代芳烃和杂芳烃提供了一种有效的合成方法。
