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隐睾山羊支持细胞的超微结构

Ultrastructure of Sertoli cells in cryptorchid goats.

作者信息

Singh A, Ezeasor D

机构信息

Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.

出版信息

Arch Androl. 1989;23(1):61-70. doi: 10.3109/01485018908986790.

DOI:10.3109/01485018908986790
PMID:2571325
Abstract

Sertoli cells of intra-abdominal testes from 25 naturally occurring, unilaterally cryptorchid, West African pygmy goats between the ages of 1-30 months were morphologically examined by light and transmission electron microscopy. Ultrastructurally, Sertoli cells in the intra-abdominal testes from 1-month-old goats were columnar and contained ovoid nuclei. The cytoplasm depicted clusters of rough endoplasmic reticulum cisternae (RER). In 3- to 4-month-old animals nucleolonemas of the Sertoli cells were associated with vesicles; the cytoplasm contained RER and areas of whorls of smooth endoplasmic reticulum. An abundance of lipid droplets was accompanied by lipofuscin granules in the cytoplasm. In 6- to 8-month-old goats RER cisternae presented circular or irregular profiles in the cells with an augmentation of cytoplasmic lipid droplets and lipofuscin granules. In 12- to 15-month-old animals intercellular spaces in the seminiferous epithelium exhibited focal expansions. Nuclear profiles of the Sertoli cells were irregular. In 24- to 30-month-old animals the Sertoli cells were in an advanced stage of degeneration.

摘要

对25只年龄在1至30个月之间自然发生单侧隐睾的西非侏儒山羊的腹腔内睾丸支持细胞进行了光镜和透射电镜形态学检查。超微结构上,1月龄山羊腹腔内睾丸的支持细胞呈柱状,细胞核呈卵圆形。细胞质中有成群的粗面内质网池(RER)。在3至4月龄的动物中,支持细胞的核仁丝与小泡相关;细胞质中含有粗面内质网和滑面内质网的漩涡区域。细胞质中有大量脂滴并伴有脂褐素颗粒。在6至8月龄的山羊中,粗面内质网池在细胞中呈现圆形或不规则形态,同时细胞质中的脂滴和脂褐素颗粒增多。在12至15月龄的动物中,生精上皮的细胞间隙出现局灶性扩张。支持细胞的核形态不规则。在24至30月龄的动物中,支持细胞处于退化的晚期阶段。

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