• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种用于微流控芯片应用的新型交流多数组电热微泵。

A novel alternating current multiple array electrothermal micropump for lab-on-a-chip applications.

机构信息

Department of Electrical and Computer Engineering, Schulich School of Engineering, University of Calgary , Calgary, Alberta T2N 1N4, Canada.

Semnan University , Semnan, Iran.

出版信息

Biomicrofluidics. 2015 Feb 6;9(1):014113. doi: 10.1063/1.4907673. eCollection 2015 Jan.

DOI:10.1063/1.4907673
PMID:25713695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4320149/
Abstract

The AC electrothermal technique is very promising for biofluid micropumping, due to its ability to pump high conductivity fluids. However, compared to electroosmotic micropumps, a lack of high fluid flow is a disadvantage. In this paper, a novel AC multiple array electrothermal (MAET) micropump, utilizing multiple microelectrode arrays placed on the side-walls of the fluidic channel of the micropump, is introduced. Asymmetric coplanar microelectrodes are placed on all sides of the microfluidic channel, and are actuated in different phases: one, two opposing, two adjacent, three, or all sides at the same time. Micropumps with different combinations of side electrodes and cross sections are numerically investigated in this paper. The effect of the governing parameters with respect to thermal, fluidic, and electrical properties are studied and discussed. To verify the simulations, the AC MAET concept was then fabricated and experimentally tested. The resulted fluid flow achieved by the experiments showed good agreement with the corresponding simulations. The number of side electrode arrays and the actuation patterns were also found to greatly influence the micropump performance. This study shows that the new multiple array electrothermal micropump design can be used in a wide range of applications such as drug delivery and lab-on-a-chip, where high flow rate and high precision micropumping devices for high conductivity fluids are needed.

摘要

交流电电热技术在生物流体微泵送方面很有前景,因为它能够泵送高电导率的流体。然而,与电渗流微泵相比,其缺乏高流量是一个缺点。在本文中,介绍了一种新颖的交流电多阵列电热(MAET)微泵,该微泵利用放置在微泵流道侧壁上的多个微电极阵列。非对称共面微电极放置在微流道的所有侧面,并以不同的相位进行激励:一个、两个相对、两个相邻、三个或所有侧面同时。本文对不同组合的侧电极和横截面的微泵进行了数值研究。研究并讨论了控制参数对热、流体和电气性能的影响。为了验证模拟,然后制造并实验测试了交流电 MAET 概念。实验得到的流体流量与相应的模拟结果吻合良好。侧电极阵列的数量和激励模式也被发现对微泵性能有很大影响。这项研究表明,新的多阵列电热微泵设计可用于广泛的应用,如药物输送和芯片实验室,在这些应用中需要用于高电导率流体的高流量和高精度微泵送设备。

相似文献

1
A novel alternating current multiple array electrothermal micropump for lab-on-a-chip applications.一种用于微流控芯片应用的新型交流多数组电热微泵。
Biomicrofluidics. 2015 Feb 6;9(1):014113. doi: 10.1063/1.4907673. eCollection 2015 Jan.
2
Simultaneous Pumping and Mixing of Biological Fluids in a Double-Array Electrothermal Microfluidic Device.双阵列电热微流控装置中生物流体的同步泵送与混合
Micromachines (Basel). 2019 Jan 28;10(2):92. doi: 10.3390/mi10020092.
3
Biofluid pumping and mixing by an AC electrothermal micropump embedded with a spiral microelectrode pair in a cylindrical microchannel.在圆柱形微通道中嵌入螺旋微电极对的交流电热微泵进行生物流体的泵送和混合。
Electrophoresis. 2018 Dec;39(24):3156-3170. doi: 10.1002/elps.201800162. Epub 2018 Sep 20.
4
Multiphase Actuation of AC Electrothermal Micropump.交流电热微泵的多相驱动
Micromachines (Basel). 2023 Mar 29;14(4):758. doi: 10.3390/mi14040758.
5
Numerical investigation of microchannel geometry for effective on-chip biofluid delivery by AC electrothermal effect.基于交流电热效应的微通道几何结构对片上生物流体输送的有效性的数值研究。
Electrophoresis. 2022 Nov;43(21-22):2130-2140. doi: 10.1002/elps.202100362. Epub 2022 May 24.
6
Bi-directional ACET micropump for on-chip biological applications.用于片上生物应用的双向交流电动微泵。
Electrophoresis. 2016 Mar;37(5-6):719-26. doi: 10.1002/elps.201500404.
7
AC electrothermal manipulation of conductive fluids and particles for lab-chip applications.用于实验室芯片应用的导电流体和颗粒的交流电热操控。
IET Nanobiotechnol. 2007 Jun;1(3):36-43. doi: 10.1049/iet-nbt:20060022.
8
Investigation of microflow reversal by ac electrokinetics in orthogonal electrodes for micropump design.正交电极中交流电动力学引起的微流动反转研究及其在微泵设计中的应用。
Biomicrofluidics. 2008 Apr 4;2(2):24101. doi: 10.1063/1.2908026.
9
Numerical Study of Particle-Fluid Flow Under AC Electrokinetics in Electrode-Multilayered Microfluidic Device.电极多层微流控装置中交流电动力学下的颗粒-流体流动的数值研究。
IEEE Trans Biomed Eng. 2019 Feb;66(2):453-463. doi: 10.1109/TBME.2018.2849004. Epub 2018 Jun 19.
10
Bi-directional flow induced by an AC electroosmotic micropump with DC voltage bias.直流偏置交流电动微泵产生的双向流动。
Electrophoresis. 2012 Apr;33(7):1191-7. doi: 10.1002/elps.201100544.

引用本文的文献

1
Microfluidic-based electrically driven particle manipulation techniques for biomedical applications.用于生物医学应用的基于微流体的电驱动粒子操控技术。
RSC Adv. 2025 Jan 3;15(1):167-198. doi: 10.1039/d4ra05571c. eCollection 2025 Jan 2.
2
Multiphase Actuation of AC Electrothermal Micropump.交流电热微泵的多相驱动
Micromachines (Basel). 2023 Mar 29;14(4):758. doi: 10.3390/mi14040758.
3
An AC electrothermal self-circulating system with a minimalist process to construct a biomimetic liver lobule model for drug testing.一种具有极简工艺流程的交流电热自循环系统,用于构建用于药物测试的仿生肝小叶模型。
RSC Adv. 2018 Nov 1;8(65):36987-36998. doi: 10.1039/c8ra03724h.
4
Rational Design and Numerical Analysis of a Hybrid Floating cIDE Separator for Continuous Dielectrophoretic Separation of Microparticles at High Throughput.用于高通量连续介电泳分离微粒的混合浮动cIDE分离器的合理设计与数值分析
Micromachines (Basel). 2022 Apr 8;13(4):582. doi: 10.3390/mi13040582.
5
Simulation of the Slip Velocity Effect in an AC Electrothermal Micropump.交流电热微泵中滑移速度效应的模拟
Micromachines (Basel). 2020 Aug 31;11(9):825. doi: 10.3390/mi11090825.
6
AC Electrothermal Effect in Microfluidics: A Review.微流控中的交流电热效应:综述
Micromachines (Basel). 2019 Nov 11;10(11):762. doi: 10.3390/mi10110762.
7
Pressure-Driven Micro-Casting for Electrode Fabrication and Its Applications in Wear Grain Detections.用于电极制造的压力驱动微铸造及其在磨粒检测中的应用
Materials (Basel). 2019 Nov 10;12(22):3710. doi: 10.3390/ma12223710.
8
Joule heating-induced particle manipulation on a microfluidic chip.微流控芯片上的焦耳热诱导粒子操控
Biomicrofluidics. 2019 Feb 22;13(1):014113. doi: 10.1063/1.5082978. eCollection 2019 Jan.
9
Simultaneous Pumping and Mixing of Biological Fluids in a Double-Array Electrothermal Microfluidic Device.双阵列电热微流控装置中生物流体的同步泵送与混合
Micromachines (Basel). 2019 Jan 28;10(2):92. doi: 10.3390/mi10020092.
10
A High-Throughput Electrokinetic Micromixer via AC Field-Effect Nonlinear Electroosmosis Control in 3D Electrode Configurations.一种通过三维电极配置中的交流场效应非线性电渗控制实现的高通量电动微混合器。
Micromachines (Basel). 2018 Aug 26;9(9):432. doi: 10.3390/mi9090432.

本文引用的文献

1
One-step surface modification for irreversible bonding of various plastics with a poly(dimethylsiloxane) elastomer at room temperature.一步法表面改性,可在室温下实现各种塑料与聚(二甲基硅氧烷)弹性体的不可逆键合。
Lab Chip. 2014 May 7;14(9):1564-71. doi: 10.1039/c3lc51324f. Epub 2014 Mar 14.
2
Study on the use of dielectrophoresis and electrothermal forces to produce on-chip micromixers and microconcentrators.基于介电泳力和电热力的片上微混合器和微浓缩器的制作研究。
Biomicrofluidics. 2012 Sep 7;6(3):34118. doi: 10.1063/1.4749827. eCollection 2012.
3
Breakup of microdroplets in asymmetric T junctions.不对称T型结中微滴的破裂。
Phys Rev E Stat Nonlin Soft Matter Phys. 2013 May;87(5):053003. doi: 10.1103/PhysRevE.87.053003. Epub 2013 May 7.
4
Enhanced electrothermal pumping with thin film resistive heaters.薄膜电阻加热器增强的电热泵送。
Electrophoresis. 2013 May;34(9-10):1400-8. doi: 10.1002/elps.201200377. Epub 2013 Apr 11.
5
Electrokinetic concentration, patterning, and sorting of colloids with thin film heaters.薄膜加热器驱动胶体的电动浓缩、图案化和分选。
J Colloid Interface Sci. 2013 Mar 15;394:598-603. doi: 10.1016/j.jcis.2012.11.066. Epub 2012 Dec 19.
6
Experimental verification of an equivalent circuit for the characterization of electrothermal micropumps: high pumping velocities induced by the external inductance at driving voltages below 5 V.电热微泵特性等效电路的实验验证:在低于 5V 的驱动电压下,外部电感可产生较高的泵送速度。
Electrophoresis. 2013 Feb;34(4):562-74. doi: 10.1002/elps.201200340. Epub 2013 Jan 24.
7
Thermally biased AC electrokinetic pumping effect for lab-on-a-chip based delivery of biofluids.基于热偏 ac 电动泵的微流控芯片生物流体输送。
Biomed Microdevices. 2013 Feb;15(1):125-33. doi: 10.1007/s10544-012-9694-z.
8
DC-biased AC-electrokinetics: a conductivity gradient driven fluid flow.直流偏置交流电动力学:一种由电导率梯度驱动的流体流动。
Lab Chip. 2011 Dec 21;11(24):4241-7. doi: 10.1039/c1lc20495e. Epub 2011 Nov 3.
9
Electrothermal Fluid Manipulation of High-Conductivity Samples for Laboratory Automation Applications.用于实验室自动化应用的高电导率样品的电热流体操控
JALA Charlottesv Va. 2010 Dec 31;15(6):426-432. doi: 10.1016/j.jala.2010.05.004.
10
AC electrothermal enhancement of heterogeneous assays in microfluidics.微流控中异质分析的交流电热增强
Lab Chip. 2007 Nov;7(11):1553-9. doi: 10.1039/b706745c. Epub 2007 Aug 10.