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[记忆的巩固、再激活和重新巩固]

[Consolidation, reactivation and reconsolidation of memory].

作者信息

Grigor'ian G A, Markevich V A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2014 Mar-Apr;64(2):123-36.

Abstract

In this review the data on consolidation and reconsolidation of memory by its reactivation (reminding) by a conditional stimulus or context are presented. A special attention is paid to "time windows" when amnesic and other interventions during memory reconsolidation become effective. The similarities and differences between consolidation of original learning and repeated consolidation (reconsolidation) during reactivation of memory by a conditional stimulus or context are considered. The hypotheses about memory updating during reconsolidation and some possible ways affecting memory are also discussed.

摘要

本综述介绍了通过条件刺激或情境对记忆进行再激活(回忆)从而实现记忆巩固和再巩固的数据。特别关注了记忆再巩固过程中失忆及其他干预措施生效的“时间窗”。文中探讨了原始学习巩固与条件刺激或情境激活记忆时的重复巩固(再巩固)之间的异同。还讨论了关于再巩固过程中记忆更新的假说以及一些影响记忆的可能方式。

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