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1型糖尿病患者如何将连续血糖监测数据转化为糖尿病管理决策。

HOW PATIENTS WITH TYPE 1 DIABETES TRANSLATE CONTINUOUS GLUCOSE MONITORING DATA INTO DIABETES MANAGEMENT DECISIONS.

作者信息

Pettus Jeremy, Price David A, Edelman Steven V

出版信息

Endocr Pract. 2015 Jun;21(6):613-20. doi: 10.4158/EP14520.OR. Epub 2015 Feb 25.

DOI:10.4158/EP14520.OR
PMID:25716635
Abstract

OBJECTIVE

To understand how patients use continuous glucose monitoring (CGM) data in their diabetes management.

METHODS

We surveyed patients who regularly used CGM (>6 days per week), using 70 questions, many scenario-based. The survey had 6 sections: patient characteristics, general CGM use, hypoglycemia prevention and management, hyperglycemia prevention and management, insulin dosing adjustments (both for incidental hyperglycemia not at meals and at mealtimes), and real-time use versus retrospective analysis.

RESULTS

The survey was completed by 222 patients with type 1 diabetes. In response to a glucose of 220 mg/dL, the average correction dose adjustment based on rate of change arrows varied dramatically. Specifically, when the CGM device showed 2 arrows up (glucose increasing >3 mg/dL/minute), respondents stated they would increase their correction bolus, on average, by 140% (range, 0 to 600%). Conversely, 2 arrows down (glucose decreasing >3 mg/dL/minute) caused respondents to reduce their dose by 42%, with 24% omitting their dose entirely. Furthermore, 59% of respondents stated they would delay a meal in response to rapidly rising glucose, whereas 60% would wait until after a meal to bolus in response to falling glucose levels. With a glucose value of 120 mg/dL and a falling glucose trend, 70% of respondents would prophylactically consume carbohydrates to avoid hypoglycemia.

CONCLUSION

CGM users utilize CGM data to alter multiple aspects of their diabetes care, including insulin dose timing, dose adjustments, and in hypoglycemia prevention. The insulin adjustments are much larger than common recommendations. Additional studies are needed to determine appropriate insulin adjustments based on glucose trend data.

摘要

目的

了解患者如何在糖尿病管理中使用连续血糖监测(CGM)数据。

方法

我们对每周规律使用CGM(>6天)的患者进行了调查,共70个问题,许多问题基于情景。该调查有6个部分:患者特征、CGM的一般使用情况、低血糖的预防和管理、高血糖的预防和管理、胰岛素剂量调整(包括针对非进餐时和进餐时的偶然高血糖情况)以及实时使用与回顾性分析。

结果

222例1型糖尿病患者完成了该调查。对于220mg/dL的血糖值,基于变化率箭头的平均校正剂量调整差异很大。具体而言,当CGM设备显示2个向上箭头(血糖升高>3mg/dL/分钟)时,受访者表示他们平均会将校正大剂量增加140%(范围为0至600%)。相反,2个向下箭头(血糖降低>3mg/dL/分钟)使受访者将剂量减少42%,其中24%完全省略剂量。此外,59%的受访者表示他们会因血糖快速上升而推迟进餐,而60%的受访者会在血糖下降时等到餐后再注射大剂量胰岛素。当血糖值为120mg/dL且血糖呈下降趋势时,70%的受访者会预防性地摄入碳水化合物以避免低血糖。

结论

CGM使用者利用CGM数据改变糖尿病护理的多个方面,包括胰岛素剂量时间、剂量调整以及低血糖预防。胰岛素调整幅度远大于常见建议。需要进一步研究以根据血糖趋势数据确定合适的胰岛素调整方法。

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