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对不孕女性的子宫腺肌病作出意外诊断。

An unexpected diagnosis of adenomyosis in the subfertile woman.

作者信息

Hunjan Tia, Davidson Andrew

机构信息

Department of Obstetrics & Gynaecology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

City Fertility Clinic, Robina, Queensland, Australia.

出版信息

BMJ Case Rep. 2015 Feb 27;2015:bcr2014209012. doi: 10.1136/bcr-2014-209012.

DOI:10.1136/bcr-2014-209012
PMID:25725032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4346970/
Abstract

A 38-year-old nulliparous female presented to an assisted conception clinic with subfertility and a long-standing history of dysmenorrhoea. Transvaginal ultrasound revealed two lesions in the body of the uterus, which were presumed to be fibroids. A decision was made to remove these lesions prior to attempting in vitro fertilisation (IVF). However, on laparotomy, deeply penetrating adenomyosis was discovered, resulting in an unexpected hysterectomy and significant blood loss. Based on our experience, we highlight the importance of suspecting a diagnosis of adenomyosis preoperatively and the methods by which this diagnosis can be made, in order to avoid potential unforeseen outcomes as described in this case. We discuss conservative management options for this condition, particularly in women wishing to preserve fertility.

摘要

一名38岁未生育的女性因生育力低下和长期痛经前往一家辅助生殖诊所就诊。经阴道超声检查发现子宫体有两个病变,推测为子宫肌瘤。决定在尝试体外受精(IVF)之前切除这些病变。然而,在剖腹手术中,发现了深部浸润性子宫腺肌病,导致意外的子宫切除术和大量失血。根据我们的经验,我们强调术前怀疑子宫腺肌病诊断的重要性以及做出该诊断的方法,以避免本病例中所述的潜在意外后果。我们讨论了这种情况的保守治疗选择,特别是对于希望保留生育能力的女性。

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An unexpected diagnosis of adenomyosis in the subfertile woman.对不孕女性的子宫腺肌病作出意外诊断。
BMJ Case Rep. 2015 Feb 27;2015:bcr2014209012. doi: 10.1136/bcr-2014-209012.
2
Treatment of adenomyomectomy in women with severe uterine adenomyosis using a novel technique.采用新技术治疗重度子宫腺肌病女性的腺肌病切除术
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本文引用的文献

1
Who will benefit from uterus-sparing surgery in adenomyosis-associated subfertility?腺肌病相关不孕患者中,哪些人将从保留子宫的手术中获益?
Fertil Steril. 2014 Sep;102(3):802-807.e1. doi: 10.1016/j.fertnstert.2014.05.028. Epub 2014 Jun 19.
2
Uterine fibroids: current perspectives.子宫肌瘤:当前观点
Int J Womens Health. 2014 Jan 29;6:95-114. doi: 10.2147/IJWH.S51083. eCollection 2014.
3
Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis.冻融胚胎移植前行垂体降调节可改善子宫腺肌病患者的妊娠结局。
Gynecol Endocrinol. 2013 Dec;29(12):1026-30. doi: 10.3109/09513590.2013.824960. Epub 2013 Sep 5.
4
Adenomyosis and subfertility: evidence of association and causation.子宫腺肌病与不孕:关联与因果关系的证据。
Semin Reprod Med. 2013 Mar;31(2):101-8. doi: 10.1055/s-0032-1333475. Epub 2013 Feb 27.
5
An update on adenomyosis.腺肌病的最新进展。
Diagn Interv Imaging. 2013 Jan;94(1):3-25. doi: 10.1016/j.diii.2012.10.012. Epub 2012 Dec 12.
6
Adenomyosis and subfertility: a systematic review of prevalence, diagnosis, treatment and fertility outcomes.腺肌病与不孕:患病率、诊断、治疗和生育结局的系统评价。
Hum Reprod Update. 2012 Jul;18(4):374-92. doi: 10.1093/humupd/dms006. Epub 2012 Mar 22.
7
Adenomyosis is a potential cause of recurrent implantation failure during IVF treatment.子宫腺肌病是体外受精治疗期间反复种植失败的一个潜在原因。
Aust N Z J Obstet Gynaecol. 2011 Jun;51(3):280-3. doi: 10.1111/j.1479-828X.2010.01276.x. Epub 2011 Jan 28.
8
MRI characteristics of the uterine junctional zone: from normal to the diagnosis of adenomyosis.子宫结合带的 MRI 特征:从正常到子宫腺肌病的诊断。
AJR Am J Roentgenol. 2011 May;196(5):1206-13. doi: 10.2214/AJR.10.4877.
9
Adenomyosis: three-dimensional sonographic findings of the junctional zone and correlation with histology.子宫腺肌病:结合带的三维超声表现及其与组织学的相关性。
Ultrasound Obstet Gynecol. 2011 Apr;37(4):471-9. doi: 10.1002/uog.8900.
10
Short-term results of magnetic resonance imaging-guided focused ultrasound surgery for patients with adenomyosis: symptomatic relief and pain reduction.磁共振引导聚焦超声手术治疗子宫腺肌病的短期疗效:症状缓解和疼痛减轻。
Fertil Steril. 2011 Mar 1;95(3):1152-5. doi: 10.1016/j.fertnstert.2010.09.024.