Oliveira Marco Aurelio Pinho, Crispi Claudio Peixoto, Brollo Leila Cristina, Crispi Claudio Peixoto, De Wilde Rudy Leon
Department of Gynecology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
, Rua Dois de Dezembro 78/803, Flamengo, Rio de Janeiro, Brazil.
Arch Gynecol Obstet. 2018 Mar;297(3):581-589. doi: 10.1007/s00404-017-4603-6. Epub 2017 Dec 2.
Adenomyosis is defined as the presence of endometrial glands and stroma within the myometrium. The true prevalence is unknown and has been reported to range from 1 to 70%. It has a significantly negative impact on women's quality of life, causing abnormal uterine bleeding, dysmenorrhea, and chronic pelvic pain. The definitive treatment for adenomyosis is hysterectomy, although it does not contemplate patients who wish to preserve their fertility. The aim of this paper is to discuss the latest evidence on the surgical techniques for the treatment of adenomyosis published in medical-scientific databases.
A comprehensive literature search for articles published from 1996 to 2017 related to surgery for adenomyosis was made in Pubmed, Medline, the Cochrane Library, and Google Scholar, in English, by the following MeSH terms: adenomyosis, surgery, pathogenesis, dysmenorrhea and infertility.
There is extensive evidence on several surgical approaches for the improvement of adenomyosis-related symptoms; however, there is no robust evidence that they are effective for infertility.
The management of adenomyosis is quite complex and controversial. Complications after extensive uterine reconstruction, such as uterine rupture, should be considered and discussed with the patient. There are still limited data to support surgery effectiveness, especially for infertility, and further well-designed studies are required.
子宫腺肌病定义为子宫肌层内存在子宫内膜腺体和间质。其真实患病率尚不清楚,据报道在1%至70%之间。它对女性生活质量有显著负面影响,可导致异常子宫出血、痛经和慢性盆腔疼痛。子宫腺肌病的 definitive 治疗方法是子宫切除术,不过这并不适用于希望保留生育能力的患者。本文旨在探讨医学科学数据库中发表的关于子宫腺肌病治疗手术技术的最新证据。
通过以下医学主题词(MeSH),于1996年至2017年在PubMed、Medline、Cochrane图书馆和谷歌学术中对与子宫腺肌病手术相关的英文文章进行全面文献检索:子宫腺肌病、手术、发病机制、痛经和不孕症。
有大量证据表明几种手术方法可改善与子宫腺肌病相关的症状;然而,尚无有力证据表明它们对不孕症有效。
子宫腺肌病的管理相当复杂且存在争议。应考虑广泛子宫重建后的并发症,如子宫破裂,并与患者进行讨论。支持手术有效性的数据仍然有限,尤其是对不孕症而言,需要进一步设计良好的研究。