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本文引用的文献

1
Generic medications in ophthalmology.眼科中的仿制药。
Br J Ophthalmol. 2013 Mar;97(3):253-7. doi: 10.1136/bjophthalmol-2012-302245. Epub 2012 Nov 9.
2
Brand name versus generic warfarin: a systematic review of the literature.品牌名药物华法林与通用名药物华法林的对比:文献系统评价。
Pharmacotherapy. 2011 Apr;31(4):386-93. doi: 10.1592/phco.31.4.386.
3
Physician perceptions about generic drugs.医生对仿制药的看法。
Ann Pharmacother. 2011 Jan;45(1):31-8. doi: 10.1345/aph.1P389. Epub 2011 Jan 4.
4
Generic drugs: the benefits and risks of making the switch.仿制药:换药的益处与风险
J Fam Pract. 2010 Nov;59(11):634-40.
5
Seizure outcomes following the use of generic versus brand-name antiepileptic drugs: a systematic review and meta-analysis.使用通用名与品牌名抗癫痫药物的癫痫发作结局:系统评价和荟萃分析。
Drugs. 2010 Mar 26;70(5):605-21. doi: 10.2165/10898530-000000000-00000.
6
Generic medicines: Greek physicians' perceptions and prescribing practices.仿制药:希腊医生的认知与处方习惯。
J Clin Pharm Ther. 2009 Oct;34(5):547-54. doi: 10.1111/j.1365-2710.2009.01037.x.
7
Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis.心血管疾病中使用的仿制药和品牌药的临床等效性:一项系统评价和荟萃分析。
JAMA. 2008 Dec 3;300(21):2514-26. doi: 10.1001/jama.2008.758.
8
A national survey on knowledge and perceptions of senior medical students in Australia about generic medicines.一项关于澳大利亚高年级医学生对非专利药品的知识和认知的全国性调查。
Med J Aust. 2008 Jan 21;188(2):123-4. doi: 10.5694/j.1326-5377.2008.tb01543.x.
9
Customers' and physicians' opinions of and experiences with generic substitution during the first year in Finland.芬兰第一年期间客户和医生对非专利药品替代的看法及体验
Health Policy. 2007 Aug;82(3):366-74. doi: 10.1016/j.healthpol.2006.10.006. Epub 2006 Dec 1.
10
[How practitioners view generic drugs: an opinion study from general practitioners in Maine-et-Loire (France)].
Therapie. 2005 Jan-Feb;60(1):67-74. doi: 10.2515/therapie:2005009.

影响家庭医生对仿制药看法的因素——一项基于问卷调查的研究

Factors affecting the opinions of family physicians regarding generic drugs--a questionnaire based study.

作者信息

Lewek Pawel, Smigielski Janusz, Kardas Przemyslaw

机构信息

Medical University of Lodz, Poland.

出版信息

Bosn J Basic Med Sci. 2014 Dec 17;15(1):45-50. doi: 10.17305/bjbms.2015.1.134.

DOI:10.17305/bjbms.2015.1.134
PMID:25725136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4365676/
Abstract

A range of factors are believed to exert a negative influence on opinions of physicians about generic drugs.The aim of this study was to survey the opinions of primary care doctors on generics, and determine the factors which may affect them. A questionnaire comprising thirty eight questions was distributed among primary care doctors working in seventy out-patient clinics of the Lodzkie province, Poland, during the period of January 1, 2010 - December 31, 2010. A total of 170 of 183 participants completed the survey (average age 48.5; 70.0% women): a 92.9% response rate. While 38.8% of physicians claimed that generics were worse than brand name drugs, 54.1% considered them to be better. However, 36.5% of the doctors did not choose generics for their own use. Two key opinions were identified among the responses concerning the effectiveness of generic drugs: use of generic drugs by the physician (p<0.001), and their opinion that pharmacists do inform patients about generic drugs (p<0.05). Although existing evidence confirms that generic and brand name drugs are equally effective, many physicians doubt this, which prevents them from being used as cost effective drug therapy. In order to increase healthcare savings through the use of generics, these factors should be addressed: for example, convincing a physician to adopt generics for personal use may be an efficient way to support more cost effective treatment of his patients.

摘要

一系列因素被认为会对医生对仿制药的看法产生负面影响。本研究的目的是调查基层医疗医生对仿制药的看法,并确定可能影响他们的因素。在2010年1月1日至2010年12月31日期间,向波兰罗兹省70家门诊诊所工作的基层医疗医生发放了一份包含38个问题的问卷。183名参与者中有170人完成了调查(平均年龄48.5岁;70.0%为女性):回复率为92.9%。虽然38.8%的医生声称仿制药比品牌药差,但54.1%的医生认为仿制药更好。然而,36.5%的医生自己不选择使用仿制药。在关于仿制药有效性的回答中确定了两个关键观点:医生对仿制药的使用(p<0.001),以及他们认为药剂师确实会告知患者有关仿制药的信息(p<0.05)。尽管现有证据证实仿制药和品牌药同样有效,但许多医生对此表示怀疑,这阻碍了仿制药被用作具有成本效益的药物治疗。为了通过使用仿制药增加医疗保健节省,应解决这些因素:例如,说服医生个人使用仿制药可能是支持更具成本效益地治疗其患者的有效方法。