Mazaud C, Chevallier B, Sigal M-L, Mahé E
Service de dermatologie, hôpital Victor-Dupouy, 69, rue du Lieutenant Colonel Prudhon, 95100 Argenteuil, France.
Service de pédiatrie, université Versailles-SQY, hôpital Ambroise-Paré, Assistance publique-Hôpitaux de Paris, 9, avenue du Général-de-Gaulle, 92100 Boulogne-Billancourt, France.
Arch Pediatr. 2015 Apr;22(4):409-13. doi: 10.1016/j.arcped.2015.01.010. Epub 2015 Feb 26.
"Eruptive nevi" is a phenomenon characterized by a rapid appearance of multiple melanocytic nevi. It is mainly developed in three groups of patients: those with systemic immunosuppression, bullous cutaneous disorders, and a melanocytic stimulation drug. We report on the case of an 11-year-old boy who was diagnosed with acute lymphoblastic leukemia. A few months after the beginning of the chemotherapy, he developed multiple pigmented lesions over the skin. Eruptive nevi syndrome has been described in the literature in 29 cases in the context of severe bullous disease and in immunosuppression. Nevi most often appear on the trunk and extremities, notably on the feet in the context of immunosuppression. They are localized in areas of bullous lesions in bullous diseases. Due to an increased melanocytic stimulation in eruptive nevi patients, long-term surveillance of individuals who have developed eruptive nevi is required, and increased sun prevention should be suggested.
“发疹性痣”是一种以多发性黑素细胞痣迅速出现为特征的现象。它主要发生在三组患者中：患有全身性免疫抑制的患者、大疱性皮肤病患者以及使用黑素细胞刺激药物的患者。我们报告一例11岁男孩，他被诊断为急性淋巴细胞白血病。化疗开始几个月后，他的皮肤上出现了多个色素沉着病变。文献中已描述了29例在严重大疱性疾病和免疫抑制背景下的发疹性痣综合征。痣最常出现在躯干和四肢，在免疫抑制情况下尤其出现在足部。在大疱性疾病中，它们位于大疱性病变区域。由于发疹性痣患者的黑素细胞刺激增加，需要对已发生发疹性痣的个体进行长期监测，并建议加强防晒。
